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19733 Rgn

19733

Rgn

regucalcin

protein-coding

Mus musculus

基因描述

Type Description
Definition regucalcin

研究结论

Date Results Publications
2020-01-25 14:08:00 Systemic ascorbic acid deficiency can be induced in GNL/SMP30-KO mice. 30827506
2019-06-29 12:14:00 In SMP30 deficient mice, colitis was significantly exacerbated as demonstrated by increased mortality (p=0.001), body weight loss (p=0.0105 at day 8), rectal bleeding (p=0.0047 at day 8) and diarrhea (p=0.0030 at day 8), histological scores (ulcers, p=0.0002; edema, p=0.0125; leukocyte infiltration, p=0.0016) and productions of pro-inflammatory cytokines (IL-1alpha, p=0.0452; IL-6, p=0.0074; G-CSF). 30266650
2018-03-31 10:04:00 It was confirmed that hair growth was significantly promoted; hair growth from hair papilla cells was also confirmed by HE staining of the shaved backs of SMP-30/GNL-KO mice in the vitamin C(+) group 28652426
2017-12-23 10:58:00 The phosphorylated eNOS and Akt levels and VEGF levels in ischemic muscle were lower in SMP30 KO and old mice than in young mice. Deficiency of SMP30 exacerbates oxidative stress related to NADPH oxidase activity enhancement and impairs eNOS activity, which leads to rarefaction of angiogenesis induced by ischemia 26912033
2016-12-17 11:53:00 Results suggested that SMP30 deficiency augments myocardial Ischemia/Reperfusion injury through reactive oxygen species generation and attenuation of Akt activation. 27077846

名称对应

Type IDs
Synonymous AI265316, GNL, SMP30
Gene
UniProtKB-ID: RGN_MOUSE
UniprotKB: Q64374
UniParc: UPI0000001925
EMBL: D86217, AL672073, U28937, U32170, AK146465, BC012710
Ensembl: ENSMUSG00000023070
KO: mmu:19733
Nucleutide sequences
EMBL-CDS: AAC52721.1, AAD03478.1, BAE27192.1, AAH12710.1, BAA13046.1
Ensembl_TRS: ENSMUST00000023832
Protein sequencees
Ensembl_PRO: ENSMUSP00000023832
RefSeq: NP_033086.1, XP_006527635.1
Others
UniRef100: UniRef100_Q64374
UniRef90: UniRef90_Q03336
UniRef50: UniRef50_Q03336
UniGene: Mm.2118
CCDS: CCDS30043.1

全选

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