| Type | Description |
|---|---|
| Definition | acyl-CoA synthetase family member 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 12:41:00 | Causal ACSF3 mutations were identified in all patients. | 30740739 |
| 2020-03-07 12:13:00 | ACSF3 catalyzes the first step of mitochondrial fatty acid biosynthesis (mtFASII). Hypofunctional mtFASII impairs mitochondrial flexibility and lipoylation degree. Defective mtFASII leads to reduced glycolytic flux and upregulation of beta-oxidation. | 31376476 |
| 2020-03-07 11:39:00 | ACSF3-derived malonyl-CoA can be used to malonylate lysine residues on proteins within the matrix of mitochondria, possibly adding another regulatory layer to post-translational control of mitochondrial metabolism. | 30201289 |
| 2017-07-22 12:33:00 | an essential role for ACSF3 in dictating the metabolic fate of mitochondrial malonate and malonyl-CoA in mammalian metabolism | 28479296 |
| 2013-07-13 11:13:00 | ACSF3 was significantly upregulated, and was involved in fatty acid and lipid metabolism and accelerated liver injury in alcoholic liver disease. | 23337955 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
ACSF3_HUMAN,
F5H5A1_HUMAN
UniprotKB:
Q4G176,
F5H5A1
UniParc:
UPI000059D3E0,
UPI00001AF19E
EMBL:
AC009113,
AK290963,
BC072391,
BC028399,
CH471184,
AC135782,
AK075499
Ensembl:
ENSG00000176715
KO:
hsa:197322
|
| Nucleutide sequences |
EMBL-CDS:
BAC11654.1,
BAF83652.1,
AAH72391.1,
AAH28399.1,
EAW66744.1
Gene_ORFName:
PSEC0197
Ensembl_TRS:
ENST00000317447,
ENST00000614302,
ENST00000406948,
ENST00000378345
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000320646,
ENSP00000479130,
ENSP00000384627,
ENSP00000367596
RefSeq:
XP_016878511.1,
XP_024305955.1,
XP_016878509.1,
XP_016878510.1,
NP_777577.2,
XP_016878508.1,
XP_024305954.1,
XP_011521245.1,
NP_001230208.1,
XP_016878507.1,
XP_005256350.1,
NP_001120686.1,
XP_011521244.1,
NP_001271245.1
|
| Others |
UniRef100:
UniRef100_Q4G176
UniRef90:
UniRef90_Q4G176
UniRef50:
UniRef50_Q4G176
UniGene:
Hs.461727,
Hs.720526
CCDS:
CCDS10974.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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