| Type | Description |
|---|---|
| Definition | ral guanine nucleotide dissociation stimulator |
| Date | Results | Publications |
|---|---|---|
| 2017-06-03 10:55:00 | In this paper, we demonstrate a potential biochemical mechanism for such phenomena by showing that c-Met receptors promote the tyrosine phosphorylation of RalGDS at Y752 in its RBD, which blocks the binding of Ras to RalGDS. | 27773821 |
| 2013-11-02 11:38:00 | Data implicate RalGDS-mediated induction of autophagy and exocyst function as a critical feature of load-induced cardiac hypertrophy. | 23473774 |
| 2010-05-10 11:16:00 | constitutive RalGEF activation had a major impact on several malignant phenotypes, particularly anchorage-independent growth, indicating that this often overlooked pathway should be more carefully evaluated as a possible therapeutic target. | 20118982 |
| 2010-01-21 00:00:00 | Results identify RalGDS as a key component in Ras-dependent carcinogenesis in vivo. | 15766660 |
| 2010-01-21 00:00:00 | we investigated the activation of RalGDS, one of the Ras effector proteins with guanine-nucleotide exchange factor activity for Ral. | 11748241 |
| Type | IDs |
|---|---|
| Synonymous | Gnds, Rgds, mKIAA1308 |
| Gene |
UniProtKB-ID:
GNDS_MOUSE,
Q6ZPU1_MOUSE,
Q3UQY9_MOUSE,
Q3TXZ3_MOUSE,
Q3TWC1_MOUSE,
A2AK33_MOUSE
UniprotKB:
Q03385,
Q6ZPU1,
Q3UQY9,
Q3TXZ3,
Q3TWC1,
A2AK33
UniParc:
UPI00005AD33A,
UPI00005AD261,
UPI0000192F42,
UPI00005AC0E1,
UPI000024DD7C,
UPI00000E6353
EMBL:
AK141959,
AK129328,
L07924,
AK159754,
CH466542,
BC027225,
AK159020,
AL772249
Ensembl:
ENSMUSG00000026821
KO:
mmu:19730
|
| Nucleutide sequences |
EMBL-CDS:
EDL08385.1,
AAA37714.1,
AAH27225.1,
BAC98138.1,
BAE24899.1,
BAE34771.1,
BAE35345.1
Ensembl_TRS:
ENSMUST00000028170,
ENSMUST00000100241,
ENSMUST00000113893
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028170,
ENSMUSP00000097812,
ENSMUSP00000109526
RefSeq:
NP_001139307.1,
XP_006497862.1,
XP_030104721.1,
XP_030104717.1,
XP_036015652.1,
XP_036015658.1,
XP_030104715.1,
NP_033084.2,
XP_006497860.1,
XP_006497859.1,
XP_006497861.1,
XP_030104714.1,
NP_001139308.1,
NP_001139306.1
|
| Others |
UniRef100:
UniRef100_Q3TXZ3,
UniRef100_Q3UQY9,
UniRef100_Q03385,
UniRef100_A2AK33,
UniRef100_Q3TWC1
UniRef90:
UniRef90_Q03385,
UniRef90_A2AK33,
UniRef90_Q03386
UniRef50:
UniRef50_Q12967
UniGene:
Mm.5236
CCDS:
CCDS15840.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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