| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 4A1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:39:00 | High intratumoral expression of eIF4A1 promotes epithelial-to-mesenchymal transition and predicts unfavorable prognosis in gastric cancer. | 32147684 |
| 2020-11-21 13:13:00 | Identification and characterization of hippuristanol-resistant mutants reveals eIF4A1 dependencies within mRNA 5' leader regions. | 32766783 |
| 2020-08-01 15:19:00 | The mRNA helicase eIF4A1 is involved in unwinding the G4 in the 5'-UTR of CtlP mRNA through its cooperation with ALC1. | 32392243 |
| 2020-06-20 12:10:00 | a number of new small molecules have been reported as having the capacity to target and inhibit eIF4A. Here, we undertook a comparative analysis of their biological activity and specificity relative to the eIF4A inhibitor, hippuristanol. | 32014999 |
| 2020-03-21 10:36:00 | remodels local 5' untranslated region structures | 31888698 |
| Type | IDs |
|---|---|
| Synonymous | DDX2A, EIF-4A, EIF4A, eIF-4A-I, eIF4A-I |
| Gene |
UniProtKB-ID:
IF4A1_HUMAN
UniprotKB:
P60842
UniParc:
UPI000006F18E,
UPI000000411B
EMBL:
BT019881,
BC009585,
AK312630,
BT019880,
AC016876,
D13748,
BC073752,
CH471108,
BC006210
Ensembl:
ENSG00000161960
KO:
hsa:1973
|
| Nucleutide sequences |
EMBL-CDS:
AAV38683.1,
BAG35515.1,
BAA02897.1,
AAV38684.1,
EAW90168.1,
AAH73752.1,
EAW90169.1,
EAW90167.1,
AAH09585.1
Ensembl_TRS:
ENST00000577269,
ENST00000293831
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000293831,
ENSP00000463486
RefSeq:
NP_001407.1,
NP_001191439.1
|
| Others |
UniRef100:
UniRef100_P60842
UniRef90:
UniRef90_P60842
UniRef50:
UniRef50_P60842
UniGene:
Hs.129673
CCDS:
CCDS11113.1,
CCDS58511.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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