A reference map of the human binary protein interactome.

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Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

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Pathogenic Variants in Fucokinase Cause a Congenital Disorder of Glycosylation.

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The fucose salvage pathway inhibits invadopodia formation and extracellular matrix degradation in melanoma cells.

PLoS ONE     Tyler Keeley , Shengchen Lin , Daniel K Lester , Eric K Lau , Shengyu Yang

Architecture of the human interactome defines protein communities and disease networks.

Nature     Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper

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Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

PLoS One     Anthony G Comuzzie , Shelley A Cole , Sandra L Laston , V Saroja Voruganti , Karin Haack , Richard A Gibbs , Nancy F Butte

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.

Brief. Bioinformatics     Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

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Complete sequencing and characterization of 21,243 full-length human cDNAs.

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