| Type | Description |
|---|---|
| Definition | tripartite motif-containing 27 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-25 12:19:00 | The roles of Trim27 in hematopoiesis were studied by enforcing its expression in mouse hematopoietic stem and progenitor cells (HSPC). Ectopic expression of Trim27 in mouse fetal liver HSPC confers repopulating advantage with myeloid dominance. Trim27 up-regulated essential regulators of myelopoiesis.The myeloproliferative advantage caused by overexpressing Trim27/TRIM27 is conserved between mouse and human hematopoiesis. | 29897614 |
| 2018-12-22 11:08:00 | Deficiency of TRIM27 significantly impairs dextran sulfate sodium (DSS)-induced activation, inflammatory cytokine expression and colitis as well as azoxymethane (AOM)/DSS-induced colitis-associated cancer in mice | 30143645 |
| 2017-06-24 10:08:00 | Trim27 connecting Slx2 may regulate meiotic processes in multiple ways by influencing XY body formation and germ cell proliferation during spermatogenesis. | 27612028 |
| 2016-11-05 11:23:00 | our study suggests that nicotine may induce murine spermatozoal apoptosis via the TNF apoptotic pathway through up-regulation of deubiquitinated RIP1 by Trim27 promoter hypomethylation. | 26607717 |
| 2016-07-30 11:05:00 | TRIM27 inhibits VSV infection-induced type I IFN production by promoting TBK1 degradation. | 26358190 |
| Type | IDs |
|---|---|
| Synonymous | AW538890, Gm19403, Rfp |
| Gene |
UniProtKB-ID:
TRI27_MOUSE
UniprotKB:
Q62158
UniParc:
UPI00000E5A54
EMBL:
L46855,
AK088180,
BC003219,
X75343
Ensembl:
ENSMUSG00000021326
KO:
mmu:19720
|
| Nucleutide sequences |
EMBL-CDS:
BAC40192.1,
CAA53092.1,
AAH03219.1,
AAA85354.1
Ensembl_TRS:
ENSMUST00000021761,
ENSMUST00000222544
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000021761,
ENSMUSP00000152730
RefSeq:
NP_033080.2,
XP_006516669.1,
XP_036013819.1
|
| Others |
UniRef100:
UniRef100_Q62158
UniRef90:
UniRef90_P14373
UniRef50:
UniRef50_P14373
UniGene:
Mm.314056
CCDS:
CCDS36607.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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