| Type | Description |
|---|---|
| Definition | REV3 like, DNA directed polymerase zeta catalytic subunit |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 12:03:00 | The roles of POLZ in DNA replication and repair have been summarized. (Review) | 31410467 |
| 2018-03-31 10:28:00 | Following challenge with AFB1, survival of mouse cells deficient in pol zeta (Rev3L(-/-)) was significantly reduced relative to Rev3L(+/-) cells or Rev3L(-/-) cells complemented through expression of the wild-type human REV3L | 27849610 |
| 2017-05-20 14:20:00 | A single aspartate mutation in the conserved catalytic site of Rev3L generates a hypomorphic phenotype in vivo and in vitro. | 27481099 |
| 2016-05-14 11:49:00 | the functions of REV3L in maintaining cell viability, embryonic viability and genomic stability are directly dependent on its polymerase activity, and cannot be ameliorated by an additional deletion of pol eta | 26727495 |
| 2013-04-27 10:32:00 | results can be unified by a model in which slowly dividing cells accumulate replication-associated DNA breaks but otherwise survive Rev3L deletion, but functional polzeta is essential for responses requiring rapid proliferation | 23386725 |
| Type | IDs |
|---|---|
| Synonymous | Rev, Rev3, Sez4 |
| Gene |
UniProtKB-ID:
REV3L_MOUSE
UniprotKB:
Q61493
UniParc:
UPI0000021751
EMBL:
D78644,
AF083464,
AC119943,
AC118733,
AB031049
Ensembl:
ENSMUSG00000019841
KO:
mmu:19714
|
| Nucleutide sequences |
EMBL-CDS:
BAA11461.1,
BAA90768.1,
AAC98785.1
Ensembl_TRS:
ENSMUST00000019986,
ENSMUST00000164763
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000131519,
ENSMUSP00000019986
RefSeq:
XP_036011601.1,
XP_006512686.1,
XP_006512685.1,
XP_036011602.1,
XP_006512687.1,
NP_035394.2
|
| Others |
UniRef100:
UniRef100_Q61493
UniRef90:
UniRef90_Q61493
UniRef50:
UniRef50_O60673
UniGene:
Mm.439723
CCDS:
CCDS23790.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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