| Type | Description |
|---|---|
| Definition | ret proto-oncogene |
| Date | Results | Publications |
|---|---|---|
| 2020-12-26 13:15:00 | RET overactivation leads to concurrent Hirschsprung disease and intestinal ganglioneuromas. | 32994173 |
| 2020-12-12 13:27:00 | Point mutagenesis in mouse reveals contrasting pathogenetic effects between MEN2B- and Hirschsprung disease-associated missense mutations of the RET gene. | 32275061 |
| 2020-10-31 13:20:00 | Acute stress disrupts intestinal homeostasis via GDNF-RET. | 32808420 |
| 2019-10-12 10:04:00 | RET can be an essential co-driver of pancreatic tumorigenesis in conjugation with KRAS activity. | 30515799 |
| 2019-09-21 12:33:00 | Removal of Ret disrupts nerve growth factor-mediated TrkA ubiquitination, leading to increased cell surface levels of TrkA, thereby potentiating survival signaling. Ret deletion significantly impairs p75 regulated intramembrane proteolysis cleavage, leading to reduced activation of downstream apoptotic effectors. | 30018091 |
| Type | IDs |
|---|---|
| Synonymous | PTC, RET51, RET9, c-Ret |
| Gene |
UniProtKB-ID:
RET_MOUSE
UniprotKB:
P35546
UniParc:
UPI00000233C4,
UPI00000EAFD5
EMBL:
X67812,
AY326397,
AK051633,
BC059012,
AF209436
Ensembl:
ENSMUSG00000030110
KO:
mmu:19713
|
| Nucleutide sequences |
EMBL-CDS:
AAF21033.1,
BAC34699.1,
AAH59012.1,
CAA48013.1,
AAP88379.1
Ensembl_TRS:
ENSMUST00000032201,
ENSMUST00000088790
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000032201,
ENSMUSP00000086169
RefSeq:
NP_001074249.1,
NP_033076.2
|
| Others |
UniRef100:
UniRef100_P35546
UniRef90:
UniRef90_P35546
UniRef50:
UniRef50_P07949
UniGene:
Mm.57199
CCDS:
CCDS39608.1,
CCDS20470.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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