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19701 Ren1

19701

Ren1

renin 1 structural

protein-coding

Mus musculus

基因描述

Type Description
Definition renin 1 structural

研究结论

Date Results Publications
2021-02-06 13:58:00 Ctcf is required for renin expression and maintenance of the structural integrity of the kidney. 32619009
2018-12-01 12:30:00 This study reveals that the human renin protein is able to complement the mouse Ren1d(-/-) non-granulated defect and suggests that granulopoiesis requires a structural motif that is conserved between the mouse Ren1d and human renin proteins. 29123029
2018-04-28 11:19:00 These observations demonstrate that activation of the renin-angiotensin system (RAS) promotes colitis in a blood pressure independent manner. Angiotensin II appears to drive colonic mucosal inflammation by promoting intestinal epithelial cell apoptosis and mucosal TH17 responses in colitis development. 27271344
2017-10-24 09:26:00 PGE2 serves as a central regulator of the Ren-1c gene in the principal cells of the kidney collecting ducts via the pathway. 28701311
2017-08-26 13:13:00 Mice homozygous for the Ren1c gene disruption (Ren1c-/-) display several morphological and physiological abnormalities, including poorly developed renal medulla, papillary atrophy, hydronephrosis, inability to concentrate the urine, polyuria, polydipsia, renal failure, and anemia. 28533331

名称对应

Type IDs
Synonymous D19352, Ren, Ren-1, Ren-A, Ren1c, Ren1d, Rn-1, Rnr
Gene
UniProtKB-ID: RENI1_MOUSE
UniprotKB: P06281
UniParc: UPI00000040C9
EMBL: X16642, X00816, X00851, K02596, X00850, X00812, X00811, AK052685, X00814, K02800, AK085309, M32352, M34190, X00810, X00815, X00813, BC061053
Ensembl: ENSMUSG00000070645
KO: mmu:19701
Nucleutide sequences
EMBL-CDS: AAH61053.1, AAA40043.1, AAA40042.1, CAA25391.1, BAC35094.1, AAA40045.1, BAC39418.1, AAA40044.1, CAA34636.1
Ensembl_TRS: ENSMUST00000094556
Protein sequencees
Ensembl_PRO: ENSMUSP00000092135
RefSeq: NP_112469.1
Others
UniRef100: UniRef100_P06281
UniRef90: UniRef90_P06281
UniRef50: UniRef50_P06281
UniGene: Mm.220955
CCDS: CCDS15295.1

全选

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