| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 2B subunit alpha |
| Date | Results | Publications |
|---|---|---|
| 2020-08-13 09:39:00 | Our results establish de novo EIF2B1 mutations as a novel cause of permanent diabetes and liver dysfunction. These findings confirm the importance of cell stress regulation for beta-cells and highlight EIF2B1's fundamental role within this pathway. | 31882561 |
| 2017-12-16 12:21:00 | Data show that eIF2Balpha and eIF2Bbeta bind to adjacent surfaces on eIF2alpha-N-terminal domains (NTDs). | 29036434 |
| 2016-05-14 11:28:00 | Oligodendrocytes with truncated or deletion mutants eIF2B showed less tolerable to endoplasmic reticulum stress | 26112719 |
| 2011-11-05 11:11:00 | These data emphasize the importance of eIF2Balpha in mediating the eIF2 kinase translation-inhibitory activity and may provide insight into the complex nature of vesiculovirus oncolysis. | 21795329 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | 20628086 |
| Type | IDs |
|---|---|
| Synonymous | EIF2B, EIF2BA |
| Gene |
UniProtKB-ID:
EI2BA_HUMAN
UniprotKB:
Q14232
UniParc:
UPI00001FB944,
UPI0000129AAE
EMBL:
CH471054,
AC117503,
AK294815,
X95648,
BC104189,
BC103763,
CR456831,
BC104188
Ensembl:
ENSG00000111361
KO:
hsa:1967
|
| Nucleutide sequences |
EMBL-CDS:
CAA64950.1,
BAG57931.1,
AAI04189.1,
CAG33112.1,
AAI03764.1,
EAW98424.1,
AAI04190.1
Ensembl_TRS:
ENST00000424014,
ENST00000537073
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000444183,
ENSP00000416250
RefSeq:
NP_001405.1
|
| Others |
UniRef100:
UniRef100_Q14232
UniRef90:
UniRef90_Q14232
UniRef50:
UniRef50_Q14232
UniGene:
Hs.741273
CCDS:
CCDS31924.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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