| Type | Description |
|---|---|
| Definition | retinol binding protein 1, cellular |
| Date | Results | Publications |
|---|---|---|
| 2019-06-29 11:57:00 | CrbpI chaperones retinol and retinal in the cell, protecting them from nonspecific oxidation and delivering them to biosynthesis enzymes where the bound (holo-) and unbound (apo-) forms of CrbpI exert distinct biological functions. Using nanoelectrospray, a native MS assay was developed for probing apo- and holo-CrbpI abundance to facilitate exploring their biological functions in in retinoid metabolism and signaling. | 27709511 |
| 2018-06-09 12:20:00 | genetic deletion of RBP1 and RBP2 did not impair synapse ultrastructure of ribbon-type synapses formed between rod bipolar cells (RBCs) and amacrine type-2 (AII) cells in the mouse retina but dramatically reduced the density of presynaptic Ca(2+) channels, decreased and desynchronized evoked neurotransmitter release | 28874522 |
| 2017-07-15 10:43:00 | RBPs perform unexpectedly broad roles at the active zone that together with those of RIMs are essential for all active zone functions. | 27537484 |
| 2015-06-20 12:44:00 | RBP1 expression was reduced in tissue and endometrial stromal cells derived from endometritis lesions versus eutopic endometruim in humans and mice. | 25143356 |
| 2013-07-06 11:24:00 | CrbpI loss disrupts all-trans retinoic acid homeostasis in mammary tissue, resulting in microenvironmental defects similar to those observed at the early stages of tumorigenesis. | 23362116 |
| Type | IDs |
|---|---|
| Synonymous | CRBPI, Crbp, Rbp-1 |
| Gene |
UniProtKB-ID:
RET1_MOUSE,
Q58EU7_MOUSE
UniprotKB:
Q00915,
Q58EU7
UniParc:
UPI0000001973
EMBL:
BC091751,
BC018254,
X60367,
AK011641
Ensembl:
ENSMUSG00000046402
KO:
mmu:19659
|
| Nucleutide sequences |
EMBL-CDS:
CAA42919.1,
AAH18254.1,
BAB27753.1,
AAH91751.1
Ensembl_TRS:
ENSMUST00000052068
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000059749
RefSeq:
NP_035384.1
|
| Others |
UniRef100:
UniRef100_Q00915
UniRef90:
UniRef90_Q00915
UniRef50:
UniRef50_Q00915
UniGene:
Mm.279741
CCDS:
CCDS23424.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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