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196527 ANO6

196527

ANO6

anoctamin 6

protein-coding

Homo sapiens

基因描述

Type Description
Definition anoctamin 6

研究结论

Date Results Publications
2021-01-16 15:58:00 Lysophosphatidic acid-induced pro-thrombotic phosphatidylserine exposure and ionophore-induced microvesiculation is mediated by the scramblase TMEM16F in erythrocytes. 32222693
2020-12-05 13:03:00 Temperature-dependent increase in the calcium sensitivity and acceleration of activation of ANO6 chloride channel variants. 31040335
2020-06-27 11:47:00 TMEM16A and TMEM16F support membrane exocytosis and are essential for plasma membrane insertion of CFTR. 30915480
2019-10-26 12:08:00 GD-N induced cell death in HEK293 and HAP1 cells was depending on expression of endogenous TMEM16F. 29463790
2019-06-15 11:02:00 Study identified an inner activation gate, which is established by three hydrophobic residues, F518, Y563 and I612, in the middle of the phospholipid permeation pathway of TMEM16F-CaPLSase. Disrupting the inner gate profoundly alters TMEM16F phospholipid permeation. 31015464

名称对应

Type IDs
Synonymous BDPLT7, SCTS, TMEM16F
Gene
UniProtKB-ID: ANO6_HUMAN, B3KX12_HUMAN
UniprotKB: Q4KMQ2, B3KX12
UniParc: UPI00004A25E3, UPI0000E595B8, UPI0000229358, UPI000022935A, UPI00018843B4
EMBL: AC009778, AC009248, BC136445, BC098410, AL833405, AC063924, AK126409
Ensembl: ENSG00000177119
KO: hsa:196527
Nucleutide sequences
EMBL-CDS: AAH98410.1, CAD38638.1, AAI36446.1, BAG54324.1
Ensembl_TRS: ENST00000425752, ENST00000441606, ENST00000423947, ENST00000320560
Protein sequencees
Ensembl_PRO: ENSP00000391417, ENSP00000413137, ENSP00000409126, ENSP00000320087
RefSeq: NP_001136150.1, NP_001191732.1, XP_005268764.1, NP_001136151.1, XP_005268763.1, NP_001020527.2
Others
UniRef100: UniRef100_Q4KMQ2, UniRef100_B3KX12
UniRef90: UniRef90_Q4KMQ2, UniRef90_B3KX12
UniRef50: UniRef50_B3KX12, UniRef50_Q4KMQ2
UniGene: Hs.505339
CCDS: CCDS44866.1, CCDS31782.1, CCDS55819.1, CCDS44865.1

全选

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