| Type | Description |
|---|---|
| Definition | RB transcriptional corepressor like 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 13:58:00 | Rb1/Rbl1/Vhl loss induces mouse subretinal angiomatous proliferation and hemangioblastoma. | 31613797 |
| 2019-07-06 13:04:00 | p107 is relevant for the metabolic activity of both brown and white adipocytes under conditions of leanness and obesity, and its deficiency is associated with increased thermogenesis and browning of WAT and hence stimulation of energy expenditure. | 30383332 |
| 2018-02-24 10:25:00 | Results show that ablation of the three members of the retinoblastoma family (RB1, p107 and p130) which targets a variety of adult lung epithelial cells, leads to spontaneous velopment of tumorlets, benign precancerous neuroendocrine (NE) lesions that do not progress to malignant tumors. Data imply the requirement of other oncogenic signaling pathways for full transformation in NE lung lesions mutant for the Rb family. | 27966456 |
| 2018-01-27 11:50:00 | the transcriptional corepressor p107 orchestrates a metabolic checkpoint that determines adipocyte lineage fates for non-committed progenitors. | 28233396 |
| 2017-10-07 12:31:00 | Findings indicate that inactivation of the Rb family proteins (Rb, p107, and p130) in hematopoietic stem cells (HSCs) progressively impairs their homeostasis, which is rescued upon repression of suppressor of cytokine signaling 3 protein (Socs3) expression in triple knockout (TKO) HSCs. | 28550162 |
| Type | IDs |
|---|---|
| Synonymous | AW547426, PRB1, p107 |
| Gene |
UniProtKB-ID:
RBL1_MOUSE,
Q6PAR4_MOUSE,
Q3UI58_MOUSE
UniprotKB:
Q64701,
Q6PAR4,
Q3UI58
UniParc:
UPI000002B223,
UPI00001EE452,
UPI0000022C6F,
UPI00001DFBC8
EMBL:
AK147064,
U27177,
AL669828,
AK156055,
U27178,
BC060124,
U33320
Ensembl:
ENSMUSG00000027641
KO:
mmu:19650
|
| Nucleutide sequences |
EMBL-CDS:
BAE33564.1,
AAB18279.1,
AAB53235.1,
AAB53236.1,
AAH60124.1,
BAE27648.1
Ensembl_TRS:
ENSMUST00000029170
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029170
RefSeq:
XP_006499081.1,
NP_001132988.1,
NP_035379.2
|
| Others |
UniRef100:
UniRef100_Q3UI58,
UniRef100_Q64701,
UniRef100_Q6PAR4
UniRef90:
UniRef90_Q3UI58,
UniRef90_P28749
UniRef50:
UniRef50_P28749,
UniRef50_A0A3Q3F9Y3
UniGene:
Mm.244671
CCDS:
CCDS16974.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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