| Type | Description |
|---|---|
| Definition | roundabout guidance receptor 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-30 10:10:00 | Our findings identify a mechanism that YTHDF1-mediated translation of m6A-modified Robo3.1 mRNA controls pre-crossing axon guidance in spinal cord | 30843071 |
| 2016-02-27 11:01:00 | This study show that this commissural neuron population includes spinal inhibitory neurons and sensory nociceptors and show that this population depends on Robo/Slit signaling yet crosses the dorsal midline in a Robo3-independent manner. | 26257608 |
| 2016-01-16 10:07:00 | These findings identify NELL2 as an axon guidance cue and establish Robo3 as a multifunctional regulator of pathfinding that simultaneously mediates NELL2 repulsion, inhibits Slit repulsion, and facilitates Netrin attraction to achieve a common guidance purpose. | 26586761 |
| 2015-04-11 11:24:00 | results suggest that Robo3 evolution was key to sculpting the mammalian brain by converting a receptor for Slit repulsion into one that both silences Slit repulsion and potentiates Netrin attraction | 25433640 |
| 2013-08-31 12:33:00 | this study demonistrated that Robo3-driven axon midline crossing conditions functional maturation of a large commissural synapse. | 23664551 |
| Type | IDs |
|---|---|
| Synonymous | Rbig1, Rig-1, Rig1, Robo3a, Robo3b |
| Gene |
UniProtKB-ID:
D3Z4M6_MOUSE
UniprotKB:
D3Z4M6
UniParc:
UPI0000D77B29
EMBL:
AC138284
Ensembl:
ENSMUSG00000032128
KO:
mmu:19649
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000115038
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000110690
RefSeq:
XP_011240727.1,
XP_036010617.1,
NP_001158239.1,
XP_011240728.1,
XP_006510170.1,
XP_011240726.1,
XP_011240729.1
|
| Others |
UniRef100:
UniRef100_D3Z4M6
UniRef90:
UniRef90_Q9Z2I4
UniRef50:
UniRef50_Q9Z2I4
UniGene:
Mm.212826
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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