EEF2KMT - eukaryotic elongation factor 2 lysine methyltransferase-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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196483 EEF2KMT

基因描述

Type	Description
Definition	eukaryotic elongation factor 2 lysine methyltransferase

研究结论

Date	Results	Publications
2015-01-03 11:36:00	Previously uncharacterized lysine-specific methyltransferase FAM86A and Yjr129c introduce a functionally important lysine methylation in eEF2.	25231979

名称对应

Type	IDs
Synonymous	EFM3, FAM86A, SB153, eEF2-KMT
Gene	UniProtKB-ID: EF2KT_HUMAN, K7ES84_HUMAN UniprotKB: Q96G04, K7ES84 UniParc: UPI0002466DAF, UPI000013D29B, UPI000006E611 EMBL: BC010084, AY037162, CH471112, AC026458 Ensembl: ENSG00000118894 KO: hsa:196483
Nucleutide sequences	EMBL-CDS: EAW85235.1, EAW85236.1, AAH10084.1, AAK67640.1 Gene_ORFName: SB153 Ensembl_TRS: ENST00000427587, ENST00000458008, ENST00000587133
Protein sequencees	Ensembl_PRO: ENSP00000389710, ENSP00000398502, ENSP00000468599 RefSeq: XP_011520706.1, NP_001275958.1, XP_005255214.1, XP_005255215.1, NP_958802.1, NP_963892.1
Others	UniRef100: UniRef100_Q96G04, UniRef100_K7ES84 UniRef90: UniRef90_Q96G04 UniRef50: UniRef50_Q96G04 UniGene: Hs.406461, Hs.592086 CCDS: CCDS10530.1, CCDS10529.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32296183	A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G CotÃ© , Meaghan Daley , Steven Deimling , Alice Desbuleux , AmÃ©lie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , IstvÃ¡n A KovÃ¡cs , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood	2020-04-01	-
31515488	Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations. Nat Commun Robert Fragoza , Jishnu Das , Shayne D Wierbowski , Jin Liang , Tina N Tran , Siqi Liang , Juan F Beltran , Christen A Rivera-Erick , Kaixiong Ye , Ting-Yi Wang , Li Yao , Matthew Mort , Peter D Stenson , David N Cooper , Xiaomu Wei , Alon Keinan , John C Schimenti , Andrew G Clark , Haiyuan Yu	2019-09-12	-
28514442	Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper	2017-05-25	-
26186194	The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin WÃ¼hr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi	2015-07-16	-
25416956	A proteome-scale map of the human interactome network. Cell Thomas Rolland , Murat TaÅan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , AmÃ©lie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , JÃ¶rg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-LÃ¡szlÃ³ BarabÃ¡si , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal	2014-11-20	-
25231979	Identification and characterization of a novel evolutionarily conserved lysine-specific methyltransferase targeting eukaryotic translation elongation factor 2 (eEF2). J Biol Chem Erna Davydova , Angela Y Y Ho , Jedrzej Malecki , Anders Moen , Jorrit M Enserink , Magnus E Jakobsson , Christoph Loenarz , PÃ¥l Ã Falnes	2014-10-31	-
23514108	Exome sequencing identifies titin mutations causing hereditary myopathy with early respiratory failure (HMERF) in families of diverse ethnic origins. BMC Neurol Camilo Toro , Montse OlivÃ© , Marinos C Dalakas , Kumaraswami Sivakumar , Juan M Bilbao , Felix Tyndel , NoemÃ Vidal , Eva Farrero , Nyamkhishig Sambuughin , Lev G Goldfarb	2013-01-01	STARD10, EEF2KMT, RTTN, TTN
23349634	A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity. PLoS Genet. Philippe Cloutier , Mathieu LavallÃ©e-Adam , Denis Faubert , Mathieu Blanchette , Benoit Coulombe	2013-01-01	PGK1, SEC53, NNT1, FUN12, CDC48, MPM1, HUWE1, LRPPRC, PDIA6, DNAJA2, TUBB3, TUBB4A, PPIH, PFDN6, CARM1, IPO7, CCT7, CCT4, CCT2, CCT6B, CCT8, HSPH1, TUBGCP2, RUVBL2, STIP1, EXOSC8, METTL23, HIST2H3C, CSTA, CTSB, METTL21A, DYNC1H1, EEF2, EEF2KMT, METTL21C, FOXK1, ALDOA, HSPA4L, KIN, CCT5, KDM1A, GANAB, EXOSC2, CASP14, HSPBP1, ETFBKMT, METTL21B, TIPRL, EIF3K, HEXB, ANXA6, DNAJA1, HSPA1A, HSPA1B, HSPA1L, HSPA2, HSPA4, HSPA5, HSPA7, HSPA8, HSPA9, HSP90AA1, HSP90AB1, HSPD1, IARS, IGBP1, TUBB8, TUBB2B, HSP90AB2P, LAMP2, LDHA, LDHB, MAT2A, MDH2, METTL1, EXOSC1, DNAJB11, PFDN1, PFDN2, PFDN4, PFDN5, POLR2H, PRMT6, FAM86C1, PPP6C, RNF126, CCDC88A, UGGT2, SAR1A, UGGT1, CCAR2, RARS, RPL3, S100A7, S100A9, TUBBP5, HNRNPCL3, FAM86B2, SNRPA1
22589738	Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. PLoS Genet Caroline S Fox , Yongmei Liu , Charles C White , Mary Feitosa , Albert V Smith , Nancy Heard-Costa , Kurt Lohman , GIANT Consortium , MAGIC Consortium , GLGC Consortium , Andrew D Johnson , Meredith C Foster , Danielle M Greenawalt , Paula Griffin , Jinghong Ding , Anne B Newman , Fran Tylavsky , Iva Miljkovic , Stephen B Kritchevsky , Lenore Launer , Melissa Garcia , Gudny Eiriksdottir , J Jeffrey Carr , Vilmunder Gudnason , Tamara B Harris , L Adrienne Cupples , Ingrid B Borecki	2012-01-01	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-

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