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1961 EGR4

1961

EGR4

early growth response 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition early growth response 4

研究结论

Date Results Publications
2020-06-20 11:20:00 our study demonstrated that the positive feedback loop between ZNF205-AS1 and EGR4 promotes non-small cell lung cancer (NSCLC) growth, and implied that targeting this feedback loop may be promising therapeutic strategy for NSCLC 30556283
2017-06-24 11:41:00 this study is the first to screen the EGR4 gene in relation to male infertility. However, our findings did not clearly explain how nonsynonymous EGR4 variations affect spermatogenesis 28464846
2015-12-26 11:58:00 EGR4 directly transactivates specific variants (V3 and V4) of the PTHrP gene resulting in subsequent transactivation of the RANKL, IL-6 and IL-8 genes via paracrine action of the PTHrP protein. 25411851
2013-01-26 10:39:00 data suggest a tendency of gender-specific association of EGR2 and EGR4 in schizophrenia. 22691714
2010-04-07 21:40:00 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) 20144677

名称对应

Type IDs
Synonymous AT133, NGFI-C, NGFIC, PAT133
Gene
UniProtKB-ID: EGR4_HUMAN, B7ZKU3_HUMAN
UniprotKB: Q05215, B7ZKU3
UniParc: UPI0000EE25D4, UPI000189A739
EMBL: BC136252, X60104, CH471053, BC143379, AC010913, X69438, AK314154
Ensembl: ENSG00000135625
KO: hsa:1961
Nucleutide sequences
EMBL-CDS: BAG36840.1, AAX88903.1, EAW99734.1, CAA49214.1, CAA42698.1, AAI43380.1, AAI36253.1
Ensembl_TRS: ENST00000545030
Protein sequencees
Ensembl_PRO: ENSP00000445626
RefSeq: NP_001956.4
Others
UniRef100: UniRef100_B7ZKU3, UniRef100_Q05215
UniRef90: UniRef90_G3QWB3, UniRef90_Q05215
UniRef50: UniRef50_Q05215
UniGene: Hs.3052

全选

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研究热度

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