| Type | Description |
|---|---|
| Definition | Kruppel-like factor 11 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:15:00 | Sclerostin antibody treatment rescues the osteopenic bone phenotype of TGFbeta inducible early gene-1 knockout female mice. | 31975377 |
| 2020-01-18 12:17:00 | Vascular smooth muscle cell-specific Klf11 knockout mice exhibited significantly reduced occlusion time.KLF11 is a novel transcriptional suppressor of F3 in vascular smooth muscle cells. KLF11 downregulates F3 at the transcriptional level as determined by reporter and chromatin immunoprecipitation assays. | 30602303 |
| 2019-02-16 12:09:00 | KLF11 acts as a novel protective factor in ischemic stroke. | 28456933 |
| 2018-04-28 10:52:00 | Consistent with loss of Klf11-mediated activation, lesions in Klf11-/- animals were associated with progressive fibrosis and decreased Drd2 expression. | 28372535 |
| 2017-10-21 11:15:00 | Using a sterile peritonitis model, fibrosis selectively developed in Klf11-/- females. Fibrosis in these animals was almost completely abrogated by ovariectomy. Ovariectomized animals were selectively supplemented with estradiol, medroxyprogesterone acetate (MPA), or dihydrotestosterone; fibrosis was only observed in mice exposed to MPA. | 28938437 |
| Type | IDs |
|---|---|
| Synonymous | 9830142A17, D12Ertd427e, Tieg2, Tieg2b, Tieg3 |
| Gene |
UniProtKB-ID:
KLF11_MOUSE
UniprotKB:
Q8K1S5
UniParc:
UPI00000EB918
EMBL:
AK050156,
AK038397,
AK084913,
BC060642,
AJ459773,
AK161233,
AK036618,
AK082838,
AK054170,
AK089044
Ensembl:
ENSMUSG00000020653
KO:
mmu:194655
|
| Nucleutide sequences |
EMBL-CDS:
BAC40717.1,
BAC34099.1,
BAC35678.1,
BAE36256.1,
BAC29984.1,
BAC38647.1,
BAC29509.1,
BAC39307.1,
AAH60642.1,
CAD30835.1
Ensembl_TRS:
ENSMUST00000020982
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000020982
RefSeq:
NP_848134.1
|
| Others |
UniRef100:
UniRef100_Q8K1S5
UniRef90:
UniRef90_Q8K1S5
UniRef50:
UniRef50_Q8K1S5
UniGene:
Mm.9616
CCDS:
CCDS25842.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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