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194388 Tet3

194388

Tet3

tet methylcytosine dioxygenase 3

protein-coding

Mus musculus

基因描述

Type Description
Definition tet methylcytosine dioxygenase 3

研究结论

Date Results Publications
2021-03-20 13:28:00 The microRNA/TET3/REST axis is required for olfactory globose basal cell proliferation and male behavior. 32677323
2021-02-27 13:50:00 TET3 controls the expression of the H3K27me3 demethylase Kdm6b during neural commitment. 32405722
2020-11-21 13:26:00 Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity. 32572241
2020-07-11 11:51:00 our results suggest that TET3 is necessary to maintain silencing of pluripotency genes and consequently neural stem cell identity, possibly through regulation of DNA methylation levels in neural precursor cells 31646359
2020-05-30 10:06:00 TET2/TET3 double-deficiency does not prevent the generation and selection of high-affinity germinal centre B cells. Rather, combined TET2 and TET3 loss-of-function in germinal centre B cells favours C-to-T and G-to-A transition mutagenesis, a finding that may be of significance for understanding the aetiology of B-cell lymphomas evolving in conditions of reduced TET function. 31120187

名称对应

Type IDs
Synonymous B430006D22Rik, BC037432, D230004J03Rik
Gene
UniProtKB-ID: TET3_MOUSE, A0A5K1VVP6_MOUSE
UniprotKB: Q8BG87, A0A5K1VVP6
UniParc: UPI00000EBA40, UPI0002A839C3, UPI00001F3A1C, UPI0002A84154
EMBL: AC159713, AK046553, BC096437, HQ423152, AK046552, AK046543, GL456132, HQ423151, AC090648, JX946278, AK044758
Ensembl: ENSMUSG00000034832
KO: mmu:194388
Nucleutide sequences
EMBL-CDS: BAC32784.1, AGB05430.1, BAC32779.1, BAC32068.1, BAC32785.1, ADR57138.1, ADR57137.1, AAH96437.1
Ensembl_TRS: ENSMUST00000186548, ENSMUST00000089622
Protein sequencees
Ensembl_PRO: ENSMUSP00000139630, ENSMUSP00000087049
RefSeq: NP_898961.2, XP_006505839.1, XP_006505838.1, XP_006505840.1, NP_001334242.1
Others
UniRef100: UniRef100_Q8BG87
UniRef90: UniRef90_Q8BG87
UniRef50: UniRef50_O43151
UniGene: Mm.211030, Mm.479194
CCDS: CCDS85071.1

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