| Type | Description |
|---|---|
| Definition | RAS protein-specific guanine nucleotide-releasing factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 12:16:00 | Cocaine self administration in RasGRF2 KO mice was increased relative to WT controls, whereas RasGRF1 KO and WT mice did not differ. RasGRF2 mediates cocaine self-administration via an ERK-dependent mechanism, whereas RasGRF1 has no effect on responding for cocaine. | 31182637 |
| 2016-12-17 11:48:00 | Nuclear migration in retinal cone photoreceptors is altered in GRF2 knockout mice. | 26743081 |
| 2015-10-17 11:56:00 | adaptations in the noradrenergic system contribute to the Rasgrf2 enhanced risk of alcoholism. | 24737505 |
| 2015-07-25 11:00:00 | Findings indicate that GRF2 regulates both the basal level and environmentally induced increase of newborn neuron survival, as well as in the induction of a distinct form of synaptic plasticity of newborn neurons that contributes to learning and memory | 24894950 |
| 2015-07-25 10:36:00 | These data suggest that Rasgrf2 controls dopaminergic signalling and adaptations to alcohol also in other brain regions, beyond the nucleus accumbens. | 25454123 |
| Type | IDs |
|---|---|
| Synonymous | 6330417G04Rik, AW048350, Grf2, Ras-GRF2 |
| Gene |
UniProtKB-ID:
RGRF2_MOUSE
UniprotKB:
P70392
UniParc:
UPI0000027079
EMBL:
U67326,
AK158472,
AH008805
KO:
mmu:19418
|
| Nucleutide sequences |
EMBL-CDS:
AAF18297.1,
AAC53058.2,
BAE34529.1
|
| Protein sequencees |
RefSeq:
XP_036013814.1,
XP_036013815.1,
NP_033053.2
|
| Others |
UniRef100:
UniRef100_P70392
UniRef90:
UniRef90_P70392
UniRef50:
UniRef50_O14827
UniGene:
Mm.248630
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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