| Type | Description |
|---|---|
| Definition | RAS, guanyl releasing protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-06-24 13:00:00 | CalDAG-GEFI is critical for atherosclerotic plaque development in hypercholesterolemic Ldlr(-/-) mice because of its contribution to platelet-leukocyte aggregate formation and leukocyte recruitment to the lesion area. | 26988592 |
| 2012-02-11 10:58:00 | (i) STIM1/SOCE is critical for procoagulant activity but not the proadhesive function of platelets; and (ii) at the site of vascular injury, STIM1 and CalDAG-GEFI are critical for the first wave of thrombin generation mediated by procoagulant platelets | 21848641 |
| 2011-10-15 11:29:00 | we evaluated the contribution of CalDAG-GEFI to platelet activation in a model of immune-mediated thrombocytopenia and thrombosis syndromes | 21652673 |
| 2011-04-16 14:21:00 | Studies indicate that CalDAG-GEFI mediates the rapid but reversible activation of integrin alphaIIbbeta3, and the adenosine diphosphate receptor P2Y12 facilitates delayed but sustained integrin activation. | 20971951 |
| 2010-09-13 11:46:00 | CalDAG-GEFI helps regulate neutrophil chemotaxis, independent of its established role in integrin activation, through a mechanism that involves actin cytoskeleton and cellular polarization. | 20413728 |
| Type | IDs |
|---|---|
| Synonymous | CDC25L, CalDAG-GEFI, Caldaggef1 |
| Gene |
UniProtKB-ID:
GRP2_MOUSE
UniprotKB:
Q9QUG9
UniParc:
UPI00004758E0,
UPI0000191054,
UPI00016277B8
EMBL:
AK034683,
U78171,
Y12339,
AF081193,
BC051474
Ensembl:
ENSMUSG00000106685,
ENSMUSG00000032946
KO:
mmu:19395
|
| Nucleutide sequences |
EMBL-CDS:
AAD12742.1,
AAC79697.1,
CAA73008.1,
AAH51474.1,
BAC28797.1
Ensembl_TRS:
ENSMUST00000201065,
ENSMUST00000201395,
ENSMUST00000200777,
ENSMUST00000200711,
ENSMUST00000200858,
ENSMUST00000202484,
ENSMUST00000113472,
ENSMUST00000035716,
ENSMUST00000167240,
ENSMUST00000113476,
ENSMUST00000113475,
ENSMUST00000113471
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000129873,
ENSMUSP00000144508,
ENSMUSP00000109104,
ENSMUSP00000109103,
ENSMUSP00000144159,
ENSMUSP00000143974,
ENSMUSP00000041135,
ENSMUSP00000144241,
ENSMUSP00000143947,
ENSMUSP00000143871,
ENSMUSP00000109100,
ENSMUSP00000109099
RefSeq:
XP_030106644.1,
XP_030106652.1,
XP_006531748.1,
XP_030106648.1,
XP_011246915.1,
XP_030106643.1,
NP_035372.2,
XP_036017360.1,
XP_011246917.1,
XP_006531749.1,
XP_030106645.1,
XP_006531750.1,
XP_006531754.1,
XP_006531753.1,
NP_001351992.1,
XP_030106647.1,
XP_006531752.1,
XP_030106646.1,
XP_030106651.1,
XP_006531751.1,
XP_030106650.1,
NP_001351991.1,
XP_006531755.1,
XP_030106649.1,
XP_036017361.1,
XP_017173571.1
|
| Others |
UniRef100:
UniRef100_Q9QUG9
UniRef90:
UniRef90_Q9QUG9
UniRef50:
UniRef50_Q9QUG9
UniGene:
Mm.77017
CCDS:
CCDS89325.1,
CCDS37898.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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||||
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