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1939 EIF2D

1939

EIF2D

eukaryotic translation initiation factor 2D

protein-coding

Homo sapiens

基因描述

Type Description
Definition eukaryotic translation initiation factor 2D

研究结论

Date Results Publications
2020-07-25 10:59:00 We observed a positive correlation trend between EIF2D mRNA levels and years of schizophrenia (SZ) disease (p=0.0794; r=0.35). We found a trend of an increase in the expression levels of EIF2D (p=0.0634) in patients suffering from the disease more than 10years compared with the SZ patients from the other subgroup . 31078689
2019-10-26 10:53:00 this is the first report which confirms the presence of ligatin and fibulin-7 in human aqueous humor, quantified their differential expression, and indicated the possibility of their involvement in the maintenance of the trabecular meshwork structure in glaucoma progression. 30958601
2019-03-02 12:25:00 a novel uORF-based regulatory mechanism that is employed under conditions of hyperosmotic stress by at least two human mRNAs, coding for translation reinitiation/recycling factor eIF2D and E3 ubiquitin ligase MDM2. This novel mode of translational control selectively downregulates their expression and requires as few as one uORF. 30419262
2018-11-10 10:55:00 Data suggest that neither eIF2A nor eIF2D are involved in the translation of this Sindbis virus subgenomic mRNA (sgmRNA) bearing non-AUG codons 28240315
2017-09-30 13:57:00 Reinitiation complexes involving initiation factors eIF2D, MCT-1, and DENR controls the translation of a large fraction of mammalian cellular mRNAs. 28732596

名称对应

Type IDs
Synonymous HCA56, LGTN
Gene
UniProtKB-ID: EIF2D_HUMAN
UniprotKB: P41214
UniParc: UPI00000710E1, UPI00003665FE
EMBL: CH471100, AF159586, BC001585, BC039134, AK001852, AF220417, AL591846, BC058905, AL162001, AF262403
Ensembl: ENSG00000143486
KO: hsa:1939
Nucleutide sequences
EMBL-CDS: AAH01585.1, BAA91942.1, AAH58905.1, CAB82330.1, AAF34185.2, EAW93536.1, AAF74205.1, EAW93540.1, AAH39134.2, AAD41909.1
Ensembl_TRS: ENST00000367114, ENST00000271764
Protein sequencees
Ensembl_PRO: ENSP00000356081, ENSP00000271764
RefSeq: XP_016856020.1, XP_005277566.1, XP_016856021.1, NP_008824.2, NP_001188407.1, XP_011507559.1, XP_011507560.1, XP_006711259.1, XP_016856019.1
Others
UniRef100: UniRef100_P41214
UniRef90: UniRef90_P41214
UniRef50: UniRef50_P41214
UniGene: Hs.497581
CCDS: CCDS1465.1, CCDS55680.1

全选

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