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19376 Rab34

19376

Rab34

RAB34, member RAS oncogene family

protein-coding

Mus musculus

基因描述

Type Description
Definition RAB34, member RAS oncogene family

研究结论

Date Results Publications
2020-01-11 11:25:00 Authors demonstrate that endocytic recycling protein Rab34 localizes to cilia, and that its mutation results in significant decrease of ciliogenesis in both cultured cells and mice. Rab34 is required for the successive fusion of preciliary vesicles to generate ciliary vesicles and for the migration of the mother centriole from perinuclear region to plasma membrane. 30301781
2018-08-18 11:44:00 CSN6 and Rab34 are involved in AR trafficking by regulating the phosphorylation signaling pathway. These findings provide new insights into the testosterone signaling pathway in Sertoli cells that mediates spermatogenesis. 29991022
2018-01-30 09:56:00 Loss-of-function mutations in the Rab34 gene lead to defects in the assembly of primary cilia, in the trafficking of proteins to primary cilia and, consequently, to impaired reception of signals from the Hedgehog pathway. 29290584
2014-06-07 11:31:00 Although Rab34 regulates both lysosomal positioning and lysosome to phagosome fusion, the latter effect is not due to the regulation of the cytoplasmic accessibility of lysosomes to phagosomes by Rab34. 23871933
2013-03-02 13:12:00 uncover Rab34/Munc13-2 as a critical part of an alternative Rab7-independent phagosome maturation machinery and lysosome-mediated killing of mycobacteria 23197834

名称对应

Type IDs
Synonymous AI326479, Narr, Rah, Rah1
Gene
UniProtKB-ID: RAB34_MOUSE, Q0PD20_MOUSE
UniprotKB: Q64008, Q0PD20
UniParc: UPI0000029672, UPI0000020C09
EMBL: AB232630, S72304, AB082927, AF322068, AL591070, AF327929, BC038638
Ensembl: ENSMUSG00000002059
KO: mmu:19376
Nucleutide sequences
EMBL-CDS: AAK09398.1, AAH38638.1, AAK11241.1, AAB20669.1, BAC16803.1, BAF02892.1
Ensembl_TRS: ENSMUST00000108322, ENSMUST00000002128
Protein sequencees
Ensembl_PRO: ENSMUSP00000103958, ENSMUSP00000002128
RefSeq: NP_001152954.1, NP_258436.2
Others
UniRef100: UniRef100_Q0PD20, UniRef100_Q64008
UniRef90: UniRef90_Q64008
UniRef50: UniRef50_Q64008
UniGene: Mm.275864
CCDS: CCDS25094.1

全选

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