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1937 EEF1G

1937

EEF1G

eukaryotic translation elongation factor 1 gamma

protein-coding

Homo sapiens

基因描述

Type Description
Definition eukaryotic translation elongation factor 1 gamma

研究结论

Date Results Publications
2019-09-07 10:18:00 study describes a novel EEF1G-ALK gene fusion in 2 pediatric patients with anaplastic large cell lymphoma that is associated with a cytoplasmic-restricted localization of the ALK fusion protein 27840423
2017-12-16 10:51:00 Results show that eEF1Bgamma binds not only Che-1 and p53 transcripts but also their promoters. Its depletion significantly decreases p53 protein accumulation and slightly impacts on Che-1 accumulation in the mitochondria. These data support the notion that eEF1Bgamma, besides its canonical role in translation, is an RNA-binding protein and a key player in cellular stress responses. 27639846
2011-07-09 11:09:00 eEF1gamma, in addition to its role in translation elongation complex, is involved in regulating Vimentin gene by contacting both pol II and the Vimentin promoter region and shuttling/nursing the Vimentin mRNA 21217813

名称对应

Type IDs
Synonymous EF1G, GIG35
Gene
UniProtKB-ID: EF1G_HUMAN, Q53YD7_HUMAN
UniprotKB: P26641, Q53YD7
UniParc: UPI00017A7F84, UPI00000012C3
EMBL: BC031012, Z11531, BC028179, BC015813, BC006509, BC021974, BC013918, AF119850, BC000384, AP002990, BC006520, BC009865, BC067738, X63526, BC007949, AY542307, M55409, CH471076, AK300203, AP001363, CR407625, BT006677
Ensembl: ENSG00000254772
KO: hsa:1937
Nucleutide sequences
EMBL-CDS: AAH06509.1, AAF69604.1, AAC18414.1, AAH28179.1, AAH06520.1, AAH31012.1, CAA45089.1, AAH21974.2, AAH07949.2, BAG61974.1, CAA77630.1, AAH09865.1, AAH67738.1, AAH13918.1, AAH15813.1, AAH00384.1, EAW74025.1, CAG28553.1, AAP35323.1, AAT08176.1
Gene_ORFName: PRO1608, hCG_2039458
Ensembl_TRS: ENST00000329251
Protein sequencees
Ensembl_PRO: ENSP00000331901
RefSeq: NP_001395.1
Others
UniRef100: UniRef100_P26641
UniRef90: UniRef90_P26641
UniRef50: UniRef50_P26641
UniGene: Hs.144835, Hs.444467
CCDS: CCDS44626.1

全选

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