| Type | Description |
|---|---|
| Definition | RAD52 homolog, DNA repair protein |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 11:33:00 | Suppression of Rad52 expression in combination with FANCM knockout drastically reduces cell and tumor growth, suggesting a synthetic lethality interaction between these two genes. | 30022024 |
| 2018-11-17 10:12:00 | Rad52 competes with Ku for binding to S-region double-strand DNA breaks (DSB) free ends, where it facilitates a DSB synaptic process, which favours intra-S region recombination. | 28176781 |
| 2018-03-10 11:52:00 | Results demonstrate that Rad52 depletion increased cell death, decreased myeloid cell frequency, and augmented the activity of CD8+ T cells and NK effectors that ultimately led to reduced tumor growth. These data provide support for the notion of RAD52 as a potential oncogene, implicating a major role for the combined processes of recombinational repair and host immunity in determining risk for Squamous Cell. | 28415565 |
| 2017-09-09 14:13:00 | In cancer-prone, heterozygous APC mutant mice, homozygous deletion of the Rad52 gene suppressed tumor growth and prolonged lifespan. | 27984746 |
| 2014-03-15 11:33:00 | Rad54 has a key function in maintaining genomic integrity of the developing germ cells. | 23949223 |
| Type | IDs |
|---|---|
| Synonymous | Rad52yh |
| Gene |
UniProtKB-ID:
RAD52_MOUSE,
G5E879_MOUSE,
Q8VEE2_MOUSE
UniprotKB:
P43352,
G5E879,
Q8VEE2
UniParc:
UPI0000478E9C,
UPI00000E5F4B,
UPI00000233F5
EMBL:
U06837,
BC019123,
Z32767,
AF004854,
AC117667,
U12135
Ensembl:
ENSMUSG00000030166
KO:
mmu:19365
|
| Nucleutide sequences |
EMBL-CDS:
CAA83659.1,
AAB69174.1,
AAA75441.1,
AAA85794.1,
AAH19123.1
Ensembl_TRS:
ENSMUST00000162461,
ENSMUST00000032269
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000125502,
ENSMUSP00000032269
RefSeq:
NP_001159853.1,
XP_006505830.1,
NP_001159854.1,
XP_006505829.1,
NP_035366.2,
XP_036021852.1,
XP_036021851.1,
XP_011239558.1,
XP_006505828.1,
NP_001159855.1,
XP_006505827.1
|
| Others |
UniRef100:
UniRef100_Q8VEE2,
UniRef100_G5E879,
UniRef100_P43352
UniRef90:
UniRef90_P43352
UniRef50:
UniRef50_P43352
UniGene:
Mm.149
CCDS:
CCDS51887.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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