| Type | Description |
|---|---|
| Definition | RAD50 double strand break repair protein |
| Date | Results | Publications |
|---|---|---|
| 2017-12-09 13:07:00 | RHS6 is a critical regulatory element for allergic airway inflammation and for coordinate regulation of Th2 cytokine genes by recruiting GATA3, SATB1, and IRF4. | 27878828 |
| 2017-10-28 13:20:00 | Low RAD50 expression is associated with B-cell lymphomas. | 28819025 |
| 2016-05-07 10:11:00 | The authors demonstrate that ATM can be activated by DNA double-strand breaks in the absence of the Mre11-Rad50-NBS1 (MRN) sensor complex. | 26280532 |
| 2014-04-26 11:40:00 | Rad50 hook domain strongly influences Mre11 complex-dependent DDR signaling, tissue homeostasis, and tumorigenesis. | 24532689 |
| 2012-02-25 10:55:00 | RAD50, DNA-PKcs kinase activity, and transcription context are each important to limit incorrect end use during EJ repair of multiple DSBs, but each has distinct roles during repair events requiring end processing | 22027841 |
| Type | IDs |
|---|---|
| Synonymous | Mrell, Rad50l |
| Gene |
UniProtKB-ID:
Q5SV02_MOUSE
UniprotKB:
Q5SV02
UniParc:
UPI00001E5A55
EMBL:
AL645741
Ensembl:
ENSMUSG00000020380
KO:
mmu:19360
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000020649
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000020649
RefSeq:
NP_033038.2
|
| Others |
UniRef100:
UniRef100_Q5SV02
UniRef90:
UniRef90_P70388
UniRef50:
UniRef50_Q92878
UniGene:
Mm.4888
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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