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19359 Rad23b

19359

Rad23b

RAD23 homolog B, nucleotide excision repair protein

protein-coding

Mus musculus

基因描述

Type Description
Definition RAD23 homolog B, nucleotide excision repair protein

研究结论

Date Results Publications
2017-09-02 13:27:00 data demonstrate that sequestration and impairment of nuclear HR23 and nucleocytoplasmic transport proteins is an outcome of, and a contributor to, poly(GA) pathology. 26998601
2012-07-14 10:33:00 the mammalian RAD23 proteins play a direct role in damage recognition by enhancing the binding of XPC to DNA damage in living cells in addition to stabilizing XPC. RAD23 proteins rapidly dissociated from XPC upon binding to damaged DNA. 22431748
2010-01-21 00:00:00 The crystal structure of the mouse peptide N-glycanase catalytic core in complex with the xeroderma pigmentosum group C binding domain from HR23B is described; the results suggest a co-evolution of ER-associated degradation and DNA repair pathways. 16500903
2010-01-21 00:00:00 This illustrates that impairment of the ubiquitin-proteasome system (UPS) by expanded glutamine repeats, including the sequestration of HR23B, is not affecting NER. 16860562
2010-01-21 00:00:00 analysis of mHR23A/B double-mutant cells showed that HR23 proteins function in nucleotide excision repair by governing xeroderma pigmentosum group C protein stability via partial protection against proteasomal degradation 12815074

名称对应

Type IDs
Synonymous 0610007D13Rik, AV001138, HR23B, mHR23B, p58
Gene
UniProtKB-ID: RD23B_MOUSE, Q3UQN3_MOUSE
UniprotKB: P54728, Q3UQN3
UniParc: UPI00005AC115, UPI0000022EA8
EMBL: X92411, AK160890, AK150089, AK160880, AK160973, AK142280, AL683890, BC027747
Ensembl: ENSMUSG00000028426
KO: mmu:19359
Nucleutide sequences
EMBL-CDS: BAE29298.1, AAH27747.1, BAE36071.1, BAE36067.1, CAA63146.1, BAE36124.1, BAE25006.1
Ensembl_TRS: ENSMUST00000030134
Protein sequencees
Ensembl_PRO: ENSMUSP00000030134
RefSeq: NP_033037.2
Others
UniRef100: UniRef100_Q3UQN3, UniRef100_P54728
UniRef90: UniRef90_P54728
UniRef50: UniRef50_P54728
UniGene: Mm.196846
CCDS: CCDS18194.1

全选

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