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19357 Rad21

19357

Rad21

RAD21 cohesin complex component

protein-coding

Mus musculus

基因描述

Type Description
Definition RAD21 cohesin complex component

研究结论

Date Results Publications
2021-01-02 12:50:00 Wapl releases Scc1-cohesin and regulates chromosome structure and segregation in mouse oocytes. 32328639
2019-11-09 12:30:00 A subset of PGP9.5- and HuC/D-IR neuronal cell bodies and nerve fibers in the myenteric plexus of human and mouse small intestine also displayed cytoplasmic RAD21 30069982
2017-12-30 10:51:00 The results demonstrate that the zygotic genome folds into loops and domains that critically depend on Scc1-cohesin and that are regulated in size and linear density by Wapl. 29217590
2017-10-14 11:36:00 n keratinocytes, the promoter-enhancer anchoring regions in the gene-rich transcriptionally active TADs are enriched for the binding of chromatin architectural proteins CTCF, Rad21 and chromatin remodeler Brg1. In contrast to gene-rich TADs, gene-poor TADs show preferential spatial contacts with each other, do not contain active enhancers and show decreased binding of CTCF, Rad21 and Brg1 in keratinocytes 28863138
2017-09-02 11:53:00 the cohesin complex regulates PRC2 targeting to silence Hoxa7 and Hoxa9 and negatively regulate self-renewal. Our studies identify a novel epigenetic mechanism underlying leukemogenesis in AML patients with cohesin mutations. 27554164

名称对应

Type IDs
Synonymous SCC1, mHR21, mKIAA0078
Gene
UniProtKB-ID: RAD21_MOUSE, Q3TG35_MOUSE
UniprotKB: Q61550, Q3TG35
UniParc: UPI00005B24E7, UPI0000021E89
EMBL: D49429, X98293, AK168896, AK163992, AK004746, AF332085, BC043032, AF332086, AK168718
Ensembl: ENSMUSG00000022314
KO: mmu:19357
Nucleutide sequences
EMBL-CDS: BAA08408.1, BAB23527.1, AAK56114.1, AAH43032.2, AAK56113.1, BAE37576.1, CAA66939.1, BAE40560.1, BAE40713.1
Ensembl_TRS: ENSMUST00000022927
Protein sequencees
Ensembl_PRO: ENSMUSP00000022927
RefSeq: XP_006520708.1, XP_006520707.1, NP_033035.3
Others
UniRef100: UniRef100_Q3TG35, UniRef100_Q61550
UniRef90: UniRef90_Q61550
UniRef50: UniRef50_Q61550
UniGene: Mm.182628
CCDS: CCDS27463.1

全选

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