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193385 Ripor2

193385

Ripor2

RHO family interacting cell polarization regulator 2

protein-coding

Mus musculus

基因描述

Type Description
Definition RHO family interacting cell polarization regulator 2

研究结论

Date Results Publications
2020-09-26 12:22:00 The FAM65B is a downstream target of Pink1 and Pink1 phosphorylates FAM65B at serine 46. Phosphorylated FAM65B inhibits autophagy and cell death in the heart. 30349076
2020-01-11 11:34:00 dysferlin deficiency seems to significantly alter the gene expression of Fam65b and Hdac6 during regeneration, since higher levels of expression of both genes were observed in dysferlin-deficient mice. 31218594
2019-11-09 12:01:00 We propose that Ripor2 deficiency influences abundance and/or post-translational modifications of proteins expressed in both stereocilia and kinocilia. This effect may have a negative impact on the structure and function of the auditory hair cell bundle. 30280293
2019-09-28 11:14:00 results show that Fam65b expression and phosphorylation can finely tune the amount of active RhoA in order to favor optimal T lymphocyte motility. 30254631
2017-11-25 13:02:00 RhoC co-localizes with Fam65b in stereocilia and regulates Fam65b oligomerization what is critical for hair cell function. 27269051

名称对应

Type IDs
Synonymous Fam65b
Gene
UniProtKB-ID: RIPR2_MOUSE, A6PW28_MOUSE, A0A5F8MPY8_MOUSE
UniprotKB: Q80U16, A6PW28, A0A5F8MPY8
UniParc: UPI00005B1FE6, UPI00000EB759, UPI00000EB756, UPI0003D72376, UPI0000EE1AC8, UPI000154A256, UPI00000EB7D8, UPI00000EB74D, UPI00000EB73A
EMBL: AK122269, AL591851, AL589744, AL513014, AK039271, AK031928, AL589699, AK041665, AK163880, AK040887, AK036452
Ensembl: ENSMUSG00000036006
KO: mmu:193385
Nucleutide sequences
EMBL-CDS: CAO77916.1, CAI25775.2, CAI25708.2, CAO77914.1, BAC31025.1, CAI26080.2, BAC65551.1, BAE37527.1, BAC27606.1, BAC30301.1, CAI25774.2, BAC29436.1, BAC30732.1, CAO77894.1
Ensembl_TRS: ENSMUST00000110384, ENSMUST00000058009, ENSMUST00000038477, ENSMUST00000091694, ENSMUST00000110383, ENSMUST00000238974
Protein sequencees
Ensembl_PRO: ENSMUSP00000043663, ENSMUSP00000051342, ENSMUSP00000089286, ENSMUSP00000106013, ENSMUSP00000106012, ENSMUSP00000159186
RefSeq: NP_848773.3, XP_006516650.1, NP_083955.1, XP_006516653.1, XP_036013808.1, XP_030103062.1, XP_006516657.1, NP_001273030.1, XP_006516652.1, XP_036013806.1, XP_006516658.1, NP_001073850.1, XP_036013809.1, XP_006516655.1, XP_006516651.1, XP_030103063.1, XP_036013807.1, XP_006516654.1, NP_001273029.1, XP_036013810.1
Others
UniRef100: UniRef100_Q80U16, UniRef100_A0A5F8MPY8, UniRef100_A6PW28
UniRef90: UniRef90_Q80U16, UniRef90_Q80U16-5
UniRef50: UniRef50_Q80U16-2, UniRef50_Q80U16
UniGene: Mm.217319
CCDS: CCDS26377.2, CCDS36623.1, CCDS36622.1

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