Rab12 - RAB12, member RAS oncogene family-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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19328 Rab12

基因描述

Type	Description
Definition	RAB12, member RAS oncogene family

研究结论

Date	Results	Publications
2016-06-11 10:40:00	we identified the small GTPase Rab12 as a novel regulator of mast cell secretory granule transport	26740112
2014-12-20 10:51:00	Dennd3 not only functions as a Rab12-GEF but also modulates Akt signaling in mouse embryonic fibroblast cells	24719330
2013-10-26 10:59:00	A new mechanism of regulation of mTORC1 signalling and autophagy, that is, quality control of PAT4 by Rab12.	23478338
2013-09-28 12:17:00	Knockdown of Rab12 increased transferrin receptor level and reduced M98K-induced cell death.	23357852
2012-02-11 10:29:00	TfR is constitutively degraded by a Rab12-dependent pathway (presumably from recycling endosomes to lysosomes), which is independent of the conventional degradation pathway.	21718402

名称对应

Type	IDs
Synonymous	2900054P15Rik, AW555448, C77700
Gene	UniProtKB-ID: RAB12_MOUSE UniprotKB: P35283 UniParc: UPI00001EB9E4 EMBL: M79303, AK013690, AB232607 Ensembl: ENSMUSG00000023460 KO: mmu:19328
Nucleutide sequences	EMBL-CDS: BAB28956.1, AAK14827.1, BAF02869.1 Ensembl_TRS: ENSMUST00000167962
Protein sequencees	Ensembl_PRO: ENSMUSP00000128645 RefSeq: XP_006523952.1, NP_077768.3
Others	UniRef100: UniRef100_P35283 UniRef90: UniRef90_P35283 UniRef50: UniRef50_P35283 UniGene: Mm.248313 CCDS: CCDS50169.1

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mRNA

Protein

UniprotKB

Description

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Pubmed编号	文献信息	发表日期	相关基因
30550785	Irisin Mediates Effects on Bone and Fat via Î±V Integrin Receptors. Cell Hyeonwoo Kim , Christiane D Wrann , Mark Jedrychowski , Sara Vidoni , Yukiko Kitase , Kenichi Nagano , Chenhe Zhou , Joshua Chou , Virginia-Jeni A Parkman , Scott J Novick , Timothy S Strutzenberg , Bruce D Pascal , Phuong T Le , Daniel J Brooks , Alexander M Roche , Kaitlyn K Gerber , Laura Mattheis , Wenjing Chen , Hua Tu , Mary L Bouxsein , Patrick R Griffin , Roland Baron , Clifford J Rosen , Lynda F Bonewald , Bruce M Spiegelman	2018-12-13	-
26740112	Rab12 Regulates Retrograde Transport of Mast Cell Secretory Granules by Interacting with the RILP-Dynein Complex. J. Immunol. Adi Efergan , Nurit P Azouz , Ofir Klein , Kenta Noguchi , Marc E Rothenberg , Mitsunori Fukuda , Ronit Sagi-Eisenberg	2016-02-01	-
24719330	Dennd3 functions as a guanine nucleotide exchange factor for small GTPase Rab12 in mouse embryonic fibroblasts. J Biol Chem Takahide Matsui , Kenta Noguchi , Mitsunori Fukuda	2014-05-16	-
23478338	Rab12 regulates mTORC1 activity and autophagy through controlling the degradation of amino-acid transporter PAT4. EMBO Rep Takahide Matsui , Mitsunori Fukuda	2013-05-01	-
23357852	M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells. Autophagy Kapil Sirohi , Madhavi Latha Somaraju Chalasani , Cherukuri Sudhakar , Asha Kumari , Vegesna Radha , Ghanshyam Swarup	2013-04-01	Rab12, Tfrc, OPTN, RAB12, RAB8A, TFRC
21718402	Small GTPase Rab12 regulates constitutive degradation of transferrin receptor. Traffic Takahide Matsui , Takashi Itoh , Mitsunori Fukuda	2011-10-01	Dennd3, Rab12, Tfrc
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
19144319	The phagosomal proteome in interferon-gamma-activated macrophages. Immunity Matthias Trost , Luc English , SÃ©bastien Lemieux , Mathieu Courcelles , Michel Desjardins , Pierre Thibault	2009-01-16	Gm21975, Ifng
18799693	Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin	2008-10-01	Gm11335, Gm17762, A930017K11Rik, BC028777, Gm13999, Gm11696, Gm12359, Gm10589, D030047H15Rik, Gm10856, Gm10685, Gm10062, Gm10433, Gm10648, Gm10840, Gm15441, Gm10684, Gm9900, Gm10822, Gm10687, Gm11744, Gm10747, Arih2os, B230344G16Rik, Fmr1os, Tmem51os1, Gm14488, Gm13033, Gm10789, Gm10615, Gm1976, Gm9967, Gm9917, Gm1974, Gm11496, Gm13580, Gm2085, Gm2183, Gm2245, Tbx3os1, Gm12980, Gm2329, Lncenc1, Gm2381, Snhg12, Gm2479, Gm12942, Gm2529, Gm2533, Rpl30-ps7, Rsf1os2, Gm2695, 2810416G20Rik, Rpl30-ps6, Gm2773, Gm2788, Dynlt1f, Gm9793, Gm2885, Gm2920, Gm15506, Gm11627, Gm10518, Gm13496, Gm3134, Gm12827, Gm3143, Gm10144, Ahnak2, Gm3196, Gm13242, Gm3325, Gm13247, Gm10863, Gm13157, 4930522L14Rik, Gm3552, Gm15226, Gm3604, Gm3643, BC005561, Gm3716, 2810410L24Rik, Gm10282, Gm3839, Nhsl2, 4732419C18Rik, Gm3906, Gm3973, Gm4013, Apol7d, Gm12057, Gm10489, Rex2, 1110002L01Rik, Gm4189, Gm4204, 4632428C04Rik, 9130023H24Rik
17967808	EUCOMM--the European conditional mouse mutagenesis program. Brief Funct Genomic Proteomic Roland H Friedel , Claudia Seisenberger , Cornelia Kaloff , Wolfgang Wurst	2007-09-01	Gm11696, Gm10589, Apela, Gm10822, Gm2085, Gm2312, Lncenc1, Gm2381, Gm2659, Gm2679, Dynlt1c, Gm3134, Gm3143, Gm3236, Gm3574, Gm3581, Gm3718, Gm3859, Gm3905, Gm3952, Gm3957, Gm3973, Gm12057, Rex2, Gm4218, Gm4225, Gm16476, Gm4407, Gm14410, Gm4420, Gm14005, 1300002E11Rik, Gm4532, Srcap, Gm17789, Gm10751, Gm14321, 0610009E02Rik, Gm12758, Gm11532, Phactr4, Rusc2, AK010878, Gm10778, 5830417I10Rik, Mir1902, Gm15270, Gm11767, Ino80dos, Bsdc1, Gm7645, Gm20590, Slc44a1, Gm15545, Gm17292, 2900009J06Rik, Kifc1, Gm13150, Gm19426, Gm19428, Gm19474, Gm14963, Gm19565, Gm19592, Gm12588, Snhg4, Gm19702, Gm19705, Platr22, Nuggc, Zfp534, Gm19860, Gm11725, Gm19876, Gm19889, Gm16201, Gm13056, Tnfsf13os, Gm19925, Gm19976, Gm20014, Gm16740, Gm20039, Gm20045, AU020206, Ccdc170, Trp53cor1, Gm20266, Gm20324, Zfp518b, Gm14401, AI480526, Pds5b, Ube3c, Gm21297, Akap9, Gm29724, Itfg2, Parp11

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