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19283 Ptprz1

19283

Ptprz1

protein tyrosine phosphatase, receptor type Z, polypeptide 1

protein-coding

Mus musculus

基因描述

Type Description
Definition protein tyrosine phosphatase, receptor type Z, polypeptide 1

研究结论

Date Results Publications
2020-09-05 13:58:00 The protein tyrosine phosphatase RPTPzeta/phosphacan is critical for perineuronal net structure. 31822561
2020-04-04 12:56:00 Ptprz knock-out mice exhibited an increased locomotor response to novelty, whereas their locomotor response to methamphetamine (METH) was reduced. Furthermore, Ptprz deficiency may reduce cell surface dopamine (DA) transporter proteins expression, thereby reducing METH-evoked DA release. 31430310
2020-02-15 11:38:00 results suggest that the extracellular region of PTPRZ, including the secretory isoform, is crucial for behavioral responses to novelty and the formation of aversive memories, whereas the PTPase activities of PTPRZ receptor isoforms are involved in regulating the dopaminergic system 31194769
2019-02-16 11:14:00 High PTPRZ1 expression is associated with glioblastoma. 28717188
2018-11-10 10:52:00 Molecular crosstalk between tumour-associated macrophages and glioma stem cells through PTN-PTPRZ1 paracrine signalling supports glioblastoma malignant growth. 28569747

名称对应

Type IDs
Synonymous AI850339, DSD-1-PG, PTPbeta, PTPzeta, Ptprz, Ptpz, R-PTP-zeta, RPTPz, Rptpbeta
Gene
UniProtKB-ID: PTPRZ_MOUSE, Q8C4M8_MOUSE, B2RXS8_MOUSE
UniprotKB: B9EKR1, Q8C4M8, B2RXS8
UniParc: UPI0001747AB8, UPI0000603B60, UPI00000E9D98
EMBL: AC134445, AK081698, BC151071, BC157965, AC133599
Ensembl: ENSMUSG00000068748
KO: mmu:19283
Nucleutide sequences
EMBL-CDS: AAI51072.1, BAC38299.1, AAI57966.1
Ensembl_TRS: ENSMUST00000090568, ENSMUST00000202102
Protein sequencees
Ensembl_PRO: ENSMUSP00000088056, ENSMUSP00000143902
RefSeq: XP_006505078.1, XP_006505076.1, XP_006505080.1, NP_001074775.1, XP_006505075.1, NP_035349.2, XP_006505077.1, NP_001348278.1, NP_001297993.1
Others
UniRef100: UniRef100_B9EKR1, UniRef100_Q8C4M8, UniRef100_B2RXS8
UniRef90: UniRef90_B2RXS8, UniRef90_Q62656
UniRef50: UniRef50_Q62656-2, UniRef50_Q62656
UniGene: Mm.41639
CCDS: CCDS39437.1

全选

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