| Type | Description |
|---|---|
| Definition | protein tyrosine phosphatase, receptor type, S |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:09:00 | LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses. | 31985401 |
| 2020-08-01 13:56:00 | Through the heparan sulfate of Nrxn1, LRRTMs recruit PTPsigma to induce presynaptic differentiation but function to varying degrees in its absence. PTPsigma forms a robust complex with Nrxn1, revealing an unexpected interaction between the two presynaptic hubs. | 31995730 |
| 2019-03-11 14:28:00 | We show that PTP-3, a LAR homolog in Caenorhabditis elegans, participates in Sema2A-regulated axon guidance. PTPdelta, a member of vertebrate LAR class PTPs, is involved in Sema3A-regulated cortical dendritic growth. In Sema3A signaling, PTPdelta activates Fyn and Src kinases by dephosphorylating their C-terminal Tyr residues. | 28637841 |
| 2019-02-09 11:21:00 | This study provides evidence that chondroitin sulfate (CS) glycosaminoglycans (GAGs) rich in 4,6-O-disulfated disaccharide units known to impede axonal growth can induce RPTPsigma clustering. | 29880643 |
| 2019-01-12 11:41:00 | Downstream molecular target of protein tyrosine phosphatase sigma (PTPsigma) modulation in oligodendrocyte progenitor cells (OPCs) involving upregulation of the protease matrix metallopeptidase 2 (MMP-2) that allows OPCs to enzymatically digest their way through chondroitin sulfate proteoglycans (CSPGs). | 30297691 |
| Type | IDs |
|---|---|
| Synonymous | AL022616, PTP, PTP-NU3, PTPNU-3, PTPsigma, Ptpt9, R-PTP-S, RPTPsigma |
| Gene |
UniProtKB-ID:
PTPRS_MOUSE,
Q3TQ52_MOUSE
UniprotKB:
B0V2N1,
Q3TQ52
UniParc:
UPI000019B062,
UPI0000443F58,
UPI000002229C,
UPI000185D574,
UPI0000484F6F,
UPI0000029F17,
UPI00005B1FEB
EMBL:
D28530,
AK163915,
BC052462,
BC083188,
AK169714,
X82288,
CT009637,
AK159320
Ensembl:
ENSMUSG00000013236
KO:
mmu:19280
|
| Nucleutide sequences |
EMBL-CDS:
AAH52462.1,
BAE34987.1,
CAA57732.1,
BAA05886.1,
AAH83188.1,
BAE41325.1,
BAE37533.1
Ensembl_TRS:
ENSMUST00000086828,
ENSMUST00000067538,
ENSMUST00000223859
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000064048,
ENSMUSP00000084038,
ENSMUSP00000153134
RefSeq:
XP_006523944.1,
XP_006523941.1,
NP_001239385.1,
XP_006523946.1,
XP_017172838.1,
XP_036016311.1,
XP_030105455.1,
XP_006523949.1,
XP_006523942.1,
XP_006523939.1,
XP_006523937.1,
XP_036016310.1,
NP_001239384.1,
XP_036016313.1,
XP_036016309.1,
XP_030105456.1,
NP_035348.2,
XP_017172839.1,
XP_036016312.1,
NP_001239382.1,
XP_006523943.1,
XP_006523940.1,
XP_006523947.1,
XP_006523938.1
|
| Others |
UniRef100:
UniRef100_B0V2N1,
UniRef100_Q3TQ52
UniRef90:
UniRef90_B0V2N1,
UniRef90_Q3TQ52
UniRef50:
UniRef50_B0V2N1,
UniRef50_Q3TQ52
UniGene:
Mm.258771
CCDS:
CCDS89125.1,
CCDS37664.1,
CCDS57103.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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