| Type | Description |
|---|---|
| Definition | Rap guanine nucleotide exchange factor (GEF) 6 |
| Date | Results | Publications |
|---|---|---|
| 2018-10-27 10:42:00 | Rapgef2-conditional knockout (cKO) mice and Rapgef6-KO mice exhibited hyperlocomotion phenotype and working-memory defect, both of which could be recognized as schizophrenia-like behavior. | 29747665 |
| 2017-11-04 10:38:00 | Study show that double knockout of Rapgef6 in Rapgef2-cKO mice (Rapgef2/6-dKO) results in marked enlargement of the ectopic cortical mass. While Rapgef2-cKO affects late-born neurons only, Rapgef2/6-dKO affects both early-born and late-born neurons in the developing brain. | 27390776 |
| 2016-03-05 10:53:00 | Rapgef6 deletion mice were impaired in hippocampal and amygdalar function and had reduced spine density and primary dendrite number in pyramidal neurons of the CA3 hippocampal region. | 26057047 |
| 2014-05-03 11:16:00 | Data indicate that the testes of RA-GEF-2(-)knockout male mice were significantly smaller than those of wild-type mice and were markedly atrophied as well as hypospermatogenic. | 24491570 |
| 2010-01-21 00:00:00 | These findings proved a crucial role of the cross-talk between two Ras-family GTPases M-Ras and Rap1, mediated by RA-GEF-2, in adhesion signaling. | 17538012 |
| Type | IDs |
|---|---|
| Synonymous | A530068K01, AI844632, BB085664, C030018K18Rik, PDZ-GEF2, Pdzgef2, RA-GEF-2, Ragef2, mKIAA4052 |
| Gene |
UniProtKB-ID:
Q8BLC8_MOUSE,
Q3TPI6_MOUSE,
B2RUJ6_MOUSE,
Q5DTR1_MOUSE,
Q3TKC6_MOUSE,
Q5NCJ1_MOUSE,
Q5NCJ0_MOUSE,
Q3UPQ2_MOUSE
UniprotKB:
Q8BLC8,
Q3TPI6,
B2RUJ6,
Q5DTR1,
Q3TKC6,
Q5NCJ1,
Q5NCJ0,
Q3UPQ2
UniParc:
UPI00005B206A,
UPI00000EB484,
UPI00005AC1D1,
UPI0001747A3C,
UPI00004E173B,
UPI000049C6E1,
UPI000049C6E0,
UPI00005B2303
EMBL:
AK045540,
AK167055,
AK220459,
AK164343,
AL607091,
AL596127,
BC141182,
AK143331
Ensembl:
ENSMUSG00000037533
KO:
mmu:192786
|
| Nucleutide sequences |
EMBL-CDS:
BAC32411.1,
BAE37750.1,
AAI41183.1,
BAD90488.1,
BAE39219.1,
BAE25343.1
Ensembl_TRS:
ENSMUST00000207429,
ENSMUST00000101206,
ENSMUST00000102743
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000147135,
ENSMUSP00000098766,
ENSMUSP00000099804
RefSeq:
XP_036012335.1,
XP_006532628.1,
XP_006532624.1,
XP_006532623.1,
NP_001239426.1,
NP_780467.2,
XP_006532626.1,
NP_001239427.1,
XP_036012336.1,
XP_006532627.1,
XP_036012337.1,
XP_006532629.1,
XP_017169837.1,
NP_001239425.1,
NP_001239423.1,
XP_006532625.1,
XP_030101557.1
|
| Others |
UniRef100:
UniRef100_Q5DTR1,
UniRef100_Q8BLC8,
UniRef100_Q5NCJ1,
UniRef100_B2RUJ6,
UniRef100_Q5NCJ0,
UniRef100_Q3TPI6
UniRef90:
UniRef90_Q3TPI6,
UniRef90_Q5NCJ1,
UniRef90_B2RUJ6,
UniRef90_Q5NCJ0,
UniRef90_Q5DTR1
UniRef50:
UniRef50_A0A673LFU9,
UniRef50_Q9Y4G8,
UniRef50_Q3TPI6,
UniRef50_Q8TEU7
UniGene:
Mm.254404
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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