| Type | Description |
|---|---|
| Definition | protein tyrosine phosphatase, receptor type, K |
| Date | Results | Publications |
|---|---|---|
| 2019-01-19 10:48:00 | Study show that RAS at the Golgi is selectively activated by apoptogenic stimuli and antagonizes cell survival by suppressing ERK activity through the induction of PTPRkappa, which targets CRAF for dephosphorylation. RAS oncogenic potential is strictly dependent on its sublocalization, with Golgi complex-located RAS antagonizing tumor development. | 30185827 |
| 2011-11-12 12:17:00 | RPTP-kappa is proteolytically processed to isoforms that have opposing effects on beta-catenin activity. | 21690299 |
| Type | IDs |
|---|---|
| Synonymous | AI853699, PTPk, RPTPkappa |
| Gene |
UniProtKB-ID:
PTPRK_MOUSE
UniprotKB:
P35822
UniParc:
UPI0000021779
EMBL:
L10106
Ensembl:
ENSMUSG00000019889
KO:
mmu:19272
|
| Nucleutide sequences |
EMBL-CDS:
AAA40021.1
Ensembl_TRS:
ENSMUST00000166468
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000126279
RefSeq:
NP_033009.1,
XP_006512680.1,
XP_006512670.1,
XP_036011592.1,
NP_001346284.1,
XP_006512674.1,
XP_006512682.1,
XP_030100820.1,
XP_006512681.1,
XP_017169339.1,
XP_006512677.1,
XP_011241448.1,
XP_011241447.1,
XP_036011597.1,
XP_006512678.1,
XP_036011596.1,
NP_001346285.1,
XP_006512671.1,
XP_036011593.1,
XP_036011594.1,
XP_006512669.1,
XP_011241446.1,
XP_011241445.1,
XP_006512675.1,
XP_006512673.1,
XP_036011595.1
|
| Others |
UniRef100:
UniRef100_P35822
UniRef90:
UniRef90_Q15262
UniRef50:
UniRef50_Q15262
UniGene:
Mm.332303
CCDS:
CCDS35874.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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