| Type | Description |
|---|---|
| Definition | elongation factor RNA polymerase II 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-09-30 12:34:00 | These results suggest that ELL2 and its pathway genes likely play an important role in the development and progression of prostate cancer. | 28870994 |
| 2015-03-07 12:20:00 | ELL2 is important for many aspects of Ab secretion, XBP1 expression, and the unfolded protein response. | 25238757 |
| 2014-10-27 12:29:00 | Deletion of the Ell2 gene in mice results in loss of Ig secretion from plasma cells and reduced expression of a number of other genes involved in secretion and the unfolded protein response like XBP1, OcaB (BOB1, Pou2af1), cyclin B2 and Ig light chain | 25238757 |
| 2013-01-05 10:45:00 | The splicing factor hnRNPLL and the transcription elongation factor ELL2 modulate the ratio of secred versus membrane-encoding Ighg2b transcripts at the expense of the secreted isoform. | 22991471 |
| 2010-01-21 00:00:00 | ELL2 enhanced both polyadenylation and exon skipping with the gene encoding the immunoglobulin heavy-chain complex (Igh) and reporter constructs | 19749764 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
ELL2_MOUSE
UniprotKB:
Q3UKU1
UniParc:
UPI00001E8846
EMBL:
AK145868,
CT025556
Ensembl:
ENSMUSG00000001542
KO:
mmu:192657
|
| Nucleutide sequences |
EMBL-CDS:
BAE26710.1
Ensembl_TRS:
ENSMUST00000001583
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000001583
RefSeq:
NP_620403.2
|
| Others |
UniRef100:
UniRef100_Q3UKU1
UniRef90:
UniRef90_Q3UKU1
UniRef50:
UniRef50_O00472
UniGene:
Mm.21288
CCDS:
CCDS36734.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30297340 |
J. Immunol. Ashley M Nelson , Nolan T Carew , Sage M Smith , Christine Milcarek |
2018-11-15 | - |
| 28870994 |
Conditional deletion of ELL2 induces murine prostate intraepithelial neoplasia. J. Endocrinol. Laura E Pascal , Khalid Z Masoodi , June Liu , Xiaonan Qiu , Qiong Song , Yujuan Wang , Yachen Zang , Tiejun Yang , Yao Wang , Lora H Rigatti , Uma Chandran , Leandro M Colli , Ricardo Z N Vencio , Yi Lu , Jian Zhang , Zhou Wang |
2017-11-01 | - |
| 28204537 |
Mitochondrial complex II regulates a distinct oxygen sensing mechanism in monocytes. Hum. Mol. Genet. Shraddha Sharma , Jianming Wang , Eduardo Cortes Gomez , Robert T Taggart , Bora E Baysal |
2017-04-01 | - |
| 27626380 |
High-throughput discovery of novel developmental phenotypes. Nature Mary E Dickinson , Ann M Flenniken , Xiao Ji , Lydia Teboul , Michael D Wong , Jacqueline K White , Terrence F Meehan , Wolfgang J Weninger , Henrik Westerberg , Hibret Adissu , Candice N Baker , Lynette Bower , James M Brown , L Brianna Caddle , Francesco Chiani , Dave Clary , James Cleak , Mark J Daly , James M Denegre , Brendan Doe , Mary E Dolan , Sarah M Edie , Helmut Fuchs , Valerie Gailus-Durner , Antonella Galli , Alessia Gambadoro , Juan Gallegos , Shiying Guo , Neil R Horner , Chih-Wei Hsu , Sara J Johnson , Sowmya Kalaga , Lance C Keith , Louise Lanoue , Thomas N Lawson , Monkol Lek , Manuel Mark , Susan Marschall , Jeremy Mason , Melissa L McElwee , Susan Newbigging , Lauryl M J Nutter , Kevin A Peterson , Ramiro Ramirez-Solis , Douglas J Rowland , Edward Ryder , Kaitlin E Samocha , John R Seavitt , Mohammed Selloum , Zsombor Szoke-Kovacs , Masaru Tamura , Amanda G Trainor , Ilinca Tudose , Shigeharu Wakana , Jonathan Warren , Olivia Wendling , David B West , Leeyean Wong , Atsushi Yoshiki , International Mouse Phenotyping Consortium , Jackson Laboratory , Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS) , Charles River Laboratories , MRC Harwell , Toronto Centre for Phenogenomics , Wellcome Trust Sanger Institute , RIKEN BioResource Center , Daniel G MacArthur , Glauco P Tocchini-Valentini , Xiang Gao , Paul Flicek , Allan Bradley , William C Skarnes , Monica J Justice , Helen E Parkinson , Mark Moore , Sara Wells , Robert E Braun , Karen L Svenson , Martin Hrabe de Angelis , Yann Herault , Tim Mohun , Ann-Marie Mallon , R Mark Henkelman , Steve D M Brown , David J Adams , K C Kent Lloyd , Colin McKerlie , Arthur L Beaudet , Maja BuÄan , Stephen A Murray |
2016-09-22 | - |
| 26398943 |
A gene expression resource generated by genome-wide lacZ profiling in the mouse. Dis Model Mech Elizabeth Tuck , Jeanne Estabel , Anika Oellrich , Anna Karin Maguire , Hibret A Adissu , Luke Souter , Emma Siragher , Charlotte Lillistone , Angela L Green , Hannah Wardle-Jones , Damian M Carragher , Natasha A Karp , Damian Smedley , Niels C Adams , Sanger Institute Mouse Genetics Project , James N Bussell , David J Adams , Ramiro RamÃrez-Solis , Karen P Steel , Antonella Galli , Jacqueline K White |
2015-11-01 | - |
| 25238757 |
J Immunol Kyung Soo Park , Ian Bayles , Alec Szlachta-McGinn , Joshua Paul , Julie Boiko , Patricia Santos , June Liu , Zhou Wang , Lisa Borghesi , Christine Milcarek |
2014-11-01 | - |
| 24146773 |
PLoS ONE Hirohito Shimizu , Atsushi Kubo , Kenta Uchibe , Megumi Hashimoto , Shigetoshi Yokoyama , Shuji Takada , Kazuhiko Mitsuoka , Hiroshi Asahara |
2013-01-01 |
Etv5,
Isl2,
Barhl2,
Kank1,
Osr2,
Ankrd1,
Pnrc1,
Nop2,
Lmx1a,
Tshz1,
Alx4,
Nr2f2,
Atf1,
Atoh1,
Bach1,
Barx1,
Prdm1,
Smyd1,
Btg2,
Runx2,
Runx1,
Runx1t1,
Cdk4,
Cdx2,
Cebpa,
Cited1,
Cnbp,
Creb3,
Ctbp2,
Dlx2,
Dlx3,
Dlx4,
Dlx5,
Arid3a,
Ebf1,
Egr1,
Emx2,
En1,
En2,
Eomes,
Epas1,
Evx2,
Eya2,
Srsf10,
Fhl2,
Foxc2,
Fli1,
Gata1,
Gata2,
Gata6,
Gbx2,
Gli1,
Gli2,
Gli3,
Aes,
Gsc,
Hand1,
Hand2,
Hes1,
Hes3,
Hes5,
Hey1,
Foxd1,
Onecut1,
Hnrnpab,
Hoxa10,
Hoxa11,
Hoxa7,
Hoxa9,
Hoxb1,
Hoxb13,
Hoxb5,
Hoxc5,
Hoxc6,
Hoxd10,
Hoxd12,
Hoxd3,
Hoxd4,
Hoxd9,
Hsp90ab1,
Elavl2,
Id3,
Irx1,
Irx2,
Irx3,
Isl1,
Jarid2,
Lef1,
Lhx1,
Lhx2,
Lhx8,
Lmo2,
Lmo4,
Lmx1b,
Mbd2,
Mcm2,
Meis1,
Meox1,
Meox2
|
| 22991471 |
Proc. Natl. Acad. Sci. U.S.A. Micah J Benson , Tarmo Aijö , Xing Chang , John Gagnon , Utz J Pape , Vivek Anantharaman , L Aravind , Juha-Pekka Pursiheimo , Shalini Oberdoerffer , X Shirley Liu , Riitta Lahesmaa , Harri Lähdesmäki , Anjana Rao |
2012-10-02 | - |
| 21677750 |
A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley |
2011-06-15 | - |
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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