| Type | Description |
|---|---|
| Definition | protein tyrosine phosphatase, receptor type, B |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 12:57:00 | The study provides evidence that PTPRB is an important regulator of TEK signaling in the aqueous humor outflow pathway, and it identifies a new therapeutic target for treatment of glaucoma. | 31621585 |
| 2020-05-09 11:04:00 | This study provides the evidence to support a model whereby VE-PTP is a driver of diabetic nephropathy and shows that VE-PTP inhibition is a promising vasculoprotective strategy for the kidney in diabetes. | 30886059 |
| 2018-08-04 11:50:00 | VEPTP (vascular endothelial protein tyrosine phosphatase) determines TIE2 response to ANGPT2. VEPTP is absent from lymphatic endothelium in mouse in vivo, permitting ANGPT2/TIE2-mediated lymphangiogenesis. | 29358379 |
| 2017-11-11 13:48:00 | PTPRB regulates branching morphogenesis in the mammary epithelium by modulating the response of the FGFR signalling pathway to FGF stimulation | 28870991 |
| 2017-08-05 10:22:00 | STIM1-induced Ca(2+) signaling activates Pyk2 to inhibit the interaction of VE-PTP and VE-cadherin and hence increase endothelial permeability. | 28385807 |
| Type | IDs |
|---|---|
| Synonymous | 3230402H02Rik, C130094E24, Ptpz, Rptpb, VE-PTP, Veptp |
| Gene |
UniProtKB-ID:
PTPRB_MOUSE,
A0A1W2P7W3_MOUSE
UniprotKB:
B2RU80,
A0A1W2P7W3
UniParc:
UPI0000F49794,
UPI000154B1C0
EMBL:
AK147668,
AC166836,
AC135862,
BC141006,
AK147439,
CH466539,
AY077755,
BC145111
Ensembl:
ENSMUSG00000020154
KO:
mmu:19263
|
| Nucleutide sequences |
EMBL-CDS:
AAI41007.1,
EDL21786.1,
AAL75813.1,
BAE27912.1,
AAI45112.1,
BAE28060.1
Ensembl_TRS:
ENSMUST00000092167,
ENSMUST00000218553
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000089805,
ENSMUSP00000151821
RefSeq:
XP_036011589.1,
XP_036011590.1,
XP_036011587.1,
NP_084204.2,
XP_036011586.1,
XP_036011591.1,
XP_036011588.1,
XP_006513441.1
|
| Others |
UniRef100:
UniRef100_B2RU80,
UniRef100_A0A1W2P7W3
UniRef90:
UniRef90_B2RU80
UniRef50:
UniRef50_B2RU80
UniGene:
Mm.37213,
Mm.489025
CCDS:
CCDS36063.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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