| Type | Description |
|---|---|
| Definition | signal-regulatory protein alpha |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:16:00 | CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis. | 32768386 |
| 2021-04-17 13:11:00 | Inflammation Unrestrained by SIRPalpha Induces Secondary Hemophagocytic Lymphohistiocytosis Independent of IFN-gamma. | 33028619 |
| 2021-03-20 13:24:00 | HSF1 promotes the viability of islet beta-cells via upregulating SIRPalpha expression. | 32141563 |
| 2021-02-20 13:30:00 | Selective SIRPalpha blockade reverses tumor T cell exclusion and overcomes cancer immunotherapy resistance. | 33074246 |
| 2021-01-16 15:54:00 | SIRPalpha on CD11c(+) cells induces Th17 cell differentiation and subsequent inflammation in the CNS in experimental autoimmune encephalomyelitis. | 32438469 |
| Type | IDs |
|---|---|
| Synonymous | AI835480, Bit, CD172a, P84, Ptpns1, SHP-1, SHPS-1, SIRP |
| Gene |
UniProtKB-ID:
SHPS1_MOUSE,
E0CX65_MOUSE,
Q6P6I8_MOUSE
UniprotKB:
P97797,
E0CX65,
Q6P6I8
UniParc:
UPI000024E726,
UPI000016C851,
UPI0001DD34A8,
UPI0000028C16,
UPI0000435046
EMBL:
AF072543,
AF072544,
AB024507,
BC062197,
AF332079,
AL808126,
AB018194,
AF332080,
CH466519,
D87967,
U89694,
D85785,
Y10349,
D87968
Ensembl:
ENSMUSG00000037902
KO:
mmu:19261
|
| Nucleutide sequences |
EMBL-CDS:
BAA13521.1,
BAA20376.1,
CAA71375.1,
AAB92591.1,
AAC24887.1,
BAA89290.1,
AAC24886.1,
BAA13520.1,
AAK56107.1,
EDL28242.1,
BAA76555.1,
BAA89289.1,
AAK56108.1,
AAH62197.1
Ensembl_TRS:
ENSMUST00000160276,
ENSMUST00000161620,
ENSMUST00000099113,
ENSMUST00000049262,
ENSMUST00000103203,
ENSMUST00000103202,
ENSMUST00000179001,
ENSMUST00000163034
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000096713,
ENSMUSP00000125004,
ENSMUSP00000049022,
ENSMUSP00000099492,
ENSMUSP00000099491,
ENSMUSP00000137611,
ENSMUSP00000124048,
ENSMUSP00000124888
RefSeq:
XP_036015585.1,
XP_017172053.1,
XP_036015589.1,
XP_036015588.1,
NP_001342087.1,
XP_017172058.1,
XP_017172057.1,
XP_030104600.1,
NP_001277948.1,
XP_036015587.1,
XP_030104598.1,
NP_031573.2,
XP_006499049.1,
NP_001277951.1,
NP_001171118.1,
NP_001277949.1,
NP_001342089.1,
NP_001277950.1,
XP_030104595.1
|
| Others |
UniRef100:
UniRef100_E0CX65,
UniRef100_Q6P6I8,
UniRef100_P97797
UniRef90:
UniRef90_P97797,
UniRef90_E0CX65
UniRef50:
UniRef50_P78324,
UniRef50_E0CX65
UniGene:
Mm.1682
CCDS:
CCDS71142.1,
CCDS16729.1,
CCDS50708.1,
CCDS71143.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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