| Type | Description |
|---|---|
| Definition | protein tyrosine phosphatase, non-receptor type 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 11:35:00 | Levels of Ptpn5 protein are elevated in a mouse model of sepsis-associated encephalopathy with associated decreases in phosphorylated forms of GluN2B, CREB, PSD95, ERK1, BDNF, and ERK2. | 31691882 |
| 2019-09-07 10:47:00 | Deletion of STEP has a beneficial effect on motor coordination and cognition in a mouse model of Huntington's disease. | 30176350 |
| 2019-07-13 11:19:00 | STEP61 undergoes proteolytic degradation in conditions leading to synaptic strengthening and memory formation | 29948948 |
| 2019-03-02 12:07:00 | activation of synaptic NMDAR by bicuculline or D-serine results in the ubiquitination and proteasomal degradation of STEP61, and increased surface localization of GluN1/GluN2B receptors. | 28466270 |
| 2018-12-22 11:35:00 | STEP plays an important role at nerve terminals in the regulation of Ca(2+) homeostasis and neurotransmitter release. | 29508281 |
| Type | IDs |
|---|---|
| Synonymous | Step |
| Gene |
UniProtKB-ID:
PTN5_MOUSE,
Q80WU9_MOUSE
UniprotKB:
P54830,
Q80WU9
UniParc:
UPI0000192678,
UPI00000E95D9,
UPI000002B1D0,
UPI00001707A0,
UPI00018E1830
EMBL:
AK038416,
S80329,
U28217,
BC079592,
U28216,
BC051975,
CH466603
Ensembl:
ENSMUSG00000030854
KO:
mmu:19259
|
| Nucleutide sequences |
EMBL-CDS:
EDL22958.1,
AAH79592.1,
AAB35656.2,
AAA73574.1,
AAA73573.1,
BAC29993.1,
AAH51975.1
Ensembl_TRS:
ENSMUST00000102626,
ENSMUST00000033142
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099686,
ENSMUSP00000033142
RefSeq:
XP_006540778.1,
XP_017177535.1,
NP_001157037.1,
NP_038671.2,
XP_006540777.1,
XP_006540776.1,
XP_030098098.1,
XP_036008691.1,
XP_036008692.1
|
| Others |
UniRef100:
UniRef100_P54830
UniRef90:
UniRef90_P54830
UniRef50:
UniRef50_P54830
UniGene:
Mm.4654
CCDS:
CCDS21294.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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