Ptpn4 - protein tyrosine phosphatase, non-receptor type 4-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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19258 Ptpn4

基因描述

Type	Description
Definition	protein tyrosine phosphatase, non-receptor type 4

研究结论

Date	Results	Publications
2015-07-04 13:00:00	our results provide new insight into the TLR4 pathway and identify PTPN4 as a specific inhibitor of TRIF-dependent TLR4 pathway.	25825441
2010-01-21 00:00:00	PTPN3 and PTPN4 are dispensable for TCR signal transduction.	19107198
2010-01-21 00:00:00	Tyrosine dephosphorylation events regulated by PTPMEG are important for both motor learning and cerebellar synaptic plasticity.	17953619

名称对应

Type	IDs
Synonymous	PTPMEG, Ptn4, TEP, TEP/mPTPMEG, hPTP-MEG
Gene	UniProtKB-ID: PTN4_MOUSE, Q8BQQ4_MOUSE UniprotKB: Q9WU22, Q8BQQ4 UniParc: UPI00000EAF03, UPI00000228B0 EMBL: CH466520, AC124760, AK046683, AF106702, AC123955 Ensembl: ENSMUSG00000026384 KO: mmu:19258
Nucleutide sequences	EMBL-CDS: AAD22773.1, EDL39812.1, BAC32836.1 Ensembl_TRS: ENSMUST00000064091
Protein sequencees	Ensembl_PRO: ENSMUSP00000067614 RefSeq: NP_064317.2, XP_030108159.1, XP_030108162.1, XP_030108161.1, XP_030108163.1, XP_006529316.1, XP_006529317.1, XP_006529319.1, XP_006529318.1
Others	UniRef100: UniRef100_Q9WU22, UniRef100_Q8BQQ4 UniRef90: UniRef90_Q9WU22, UniRef90_E9Q0S8 UniRef50: UniRef50_Q9WU22, UniRef50_E9Q0S8 UniGene: Mm.458796 CCDS: CCDS15227.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32325033	BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili	2020-04-22	-
25424712	Deletion of protein tyrosine phosphatase, non-receptor type 4 (PTPN4) in twins with a Rett syndrome-like phenotype. Eur. J. Hum. Genet. Sarah L Williamson , Carolyn J Ellaway , Greg B Peters , Gregory J Pelka , Patrick P L Tam , John Christodoulou	2015-09-01	-
25825441	Phosphatase PTPN4 preferentially inhibits TRIF-dependent TLR4 pathway by dephosphorylating TRAM. J Immunol Wanwan Huai , Hui Song , Lijuan Wang , Bingqing Li , Jing Zhao , Lihui Han , Chengjiang Gao , Guosheng Jiang , Lining Zhang , Wei Zhao	2015-05-01	-
23431139	The Î´2 glutamate receptor gates long-term depression by coordinating interactions between two AMPA receptor phosphorylation sites. Proc. Natl. Acad. Sci. U.S.A. Kazuhisa Kohda , Wataru Kakegawa , Shinji Matsuda , Tadashi Yamamoto , Hisashi Hirano , Michisuke Yuzaki	2013-03-05	Grid2, Ptpn4
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21267068	A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja NÃ¼rnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal DollÃ© , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio	2011-01-18	-
18799693	Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin	2008-10-01	Gm11335, Gm17762, A930017K11Rik, BC028777, Gm13999, Gm11696, Gm12359, Gm10589, D030047H15Rik, Gm10856, Gm10685, Gm10062, Gm10433, Gm10648, Gm10840, Gm15441, Gm10684, Gm9900, Gm10822, Gm10687, Gm11744, Gm10747, Arih2os, B230344G16Rik, Fmr1os, Tmem51os1, Gm14488, Gm13033, Gm10789, Gm10615, Gm1976, Gm9967, Gm9917, Gm1974, Gm11496, Gm13580, Gm2085, Gm2183, Gm2245, Tbx3os1, Gm12980, Gm2329, Lncenc1, Gm2381, Snhg12, Gm2479, Gm12942, Gm2529, Gm2533, Rpl30-ps7, Rsf1os2, Gm2695, 2810416G20Rik, Rpl30-ps6, Gm2773, Gm2788, Dynlt1f, Gm9793, Gm2885, Gm2920, Gm15506, Gm11627, Gm10518, Gm13496, Gm3134, Gm12827, Gm3143, Gm10144, Ahnak2, Gm3196, Gm13242, Gm3325, Gm13247, Gm10863, Gm13157, 4930522L14Rik, Gm3552, Gm15226, Gm3604, Gm3643, BC005561, Gm3716, 2810410L24Rik, Gm10282, Gm3839, Nhsl2, 4732419C18Rik, Gm3906, Gm3973, Gm4013, Apol7d, Gm12057, Gm10489, Rex2, 1110002L01Rik, Gm4189, Gm4204, 4632428C04Rik, 9130023H24Rik
18614237	The protein tyrosine phosphatase PTPN4/PTP-MEG1, an enzyme capable of dephosphorylating the TCR ITAMs and regulating NF-kappaB, is dispensable for T cell development and/or T cell effector functions. Mol. Immunol. Jennifer A Young , Amy M Becker , Jennifer J Medeiros , Virginia S Shapiro , Andrew Wang , J David Farrar , Timothy A Quill , Rob Hooft van Huijsduijnen , Nicolai S C van Oers	2008-08-01	Cd247, Meox2, Ptpn4, PTPN4
19107198	The FERM and PDZ domain-containing protein tyrosine phosphatases, PTPN4 and PTPN3, are both dispensable for T cell receptor signal transduction. PLoS ONE Timothy J Bauler , Wiljan J A J Hendriks , Philip D King	2008-01-01	Ptpn13, Ptpn4, Ptpn3
17953619	Involvement of protein-tyrosine phosphatase PTPMEG in motor learning and cerebellar long-term depression. Eur. J. Neurosci. Shin-ichiro Kina , Tohru Tezuka , Shinji Kusakawa , Yasushi Kishimoto , Sho Kakizawa , Koichi Hashimoto , Miho Ohsugi , Yuji Kiyama , Reiko Horai , Katsuko Sudo , Shigeru Kakuta , Yoichiro Iwakura , Masamitsu Iino , Masanobu Kano , Toshiya Manabe , Tadashi Yamamoto	2007-10-01	Ptpn4

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