| Type | Description |
|---|---|
| Definition | protein tyrosine phosphatase, non-receptor type 13 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-12 11:13:00 | Both in its ligand-free state and when bind to PRK2, PDZ3 of PTPN13 adopts the classical compact, globular D/E fold. PDZ3 of PTPN13 binds five carboxy-terminal amino acids of PRK2 via a groove located between the EB-strand and the DB-helix. | 30189200 |
| 2019-06-29 11:07:00 | Following TBI, calpain-2 activation cleaved PTPN13, activated c-Abl and triggered tau tyrosine phosphorylation. | 28924170 |
| 2017-07-29 10:49:00 | contributions of Fap1 to tyrosine kinase inhibitors (TKI)resistance, CML blast crisis, and relapse after TKI discontinuation | 26984787 |
| 2016-08-06 10:46:00 | The data show that the levels of PTPN13 and beta-catenin must be strictly regulated by extracellular signaling to regulate hematopoietic stem cells attachment to the bone marrow niche and the balance between proliferation and quiescence. | 26344907 |
| 2015-04-04 12:32:00 | The study presents a detailed kinetics analysis of the interaction between PTP-BL PDZ2 domain and a peptide mimicking the PDZ binding motif of APC. | 24928580 |
| Type | IDs |
|---|---|
| Synonymous | AI324989, PTP-BL, PTPL1, Ptpri, RIP |
| Gene |
UniProtKB-ID:
PTN13_MOUSE,
Q8BV52_MOUSE,
Q3TPD6_MOUSE,
Q3TTT8_MOUSE,
G5E8B1_MOUSE
UniprotKB:
Q64512,
Q8BV52,
Q3TPD6,
Q3TTT8,
G5E8B1
UniParc:
UPI00000EA964,
UPI00005B1CFE,
UPI00005B2086,
UPI00001F328C,
UPI0000252359
EMBL:
Z32740,
AC157551,
AK161200,
AK164471,
AC161169,
Z23059,
D28529,
AK080313,
D83966
Ensembl:
ENSMUSG00000034573
KO:
mmu:19249
|
| Nucleutide sequences |
EMBL-CDS:
BAA05885.1,
BAA12158.1,
CAA83650.1,
CAA80594.1,
BAC37876.1,
BAE37800.1,
BAE36236.1
Ensembl_TRS:
ENSMUST00000048957
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000048119
RefSeq:
NP_035334.2
|
| Others |
UniRef100:
UniRef100_Q3TTT8,
UniRef100_G5E8B1,
UniRef100_Q64512,
UniRef100_Q8BV52
UniRef90:
UniRef90_Q3TTT8,
UniRef90_Q64512,
UniRef90_Q8BV52
UniRef50:
UniRef50_A0A673HS99,
UniRef50_Q12923,
UniRef50_Q3TTT8
UniGene:
Mm.3414
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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