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19247 Ptpn11

19247

Ptpn11

protein tyrosine phosphatase, non-receptor type 11

protein-coding

Mus musculus

基因描述

Type Description
Definition protein tyrosine phosphatase, non-receptor type 11

研究结论

Date Results Publications
2021-01-16 15:55:00 Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels. 32546483
2021-01-16 15:54:00 The Noonan syndrome-associated D61G variant of the protein tyrosine phosphatase SHP2 prevents synaptic down-scaling. 32499374
2021-01-16 15:53:00 Upregulated SHP-2 expression in the epileptogenic zone of temporal lobe epilepsy and various effects of SHP099 treatment on a pilocarpine model. 31398269
2020-12-12 13:25:00 The immune checkpoint receptor associated phosphatases SHP-1 and SHP-2 are not required for gammadeltaT17 cell development, activation, or skin inflammation. 32092146
2020-12-05 13:02:00 The role of tyrosine phosphatase Shp2 in spermatogonial differentiation and spermatocyte meiosis. 31210146

名称对应

Type IDs
Synonymous 2700084A17Rik, AW536184, PTP1D, PTP2C, SAP-2, SH-PTP2, SH-PTP3, SHP-2, Shp2, Syp
Gene
UniProtKB-ID: PTN11_MOUSE
UniprotKB: P35235
UniParc: UPI00000E5F18, UPI00001D6FC1
EMBL: AK159501, AK163809, D84372, BC057398, BC059278, AK159587, L08663
Ensembl: ENSMUSG00000043733
KO: mmu:19247
Nucleutide sequences
EMBL-CDS: AAH59278.1, AAH57398.1, BAA12328.1, BAE35134.1, BAE37500.1, BAE35207.1
Ensembl_TRS: ENSMUST00000100770, ENSMUST00000054547
Protein sequencees
Ensembl_PRO: ENSMUSP00000058757, ENSMUSP00000098333
RefSeq: NP_001103462.1, NP_035332.1
Others
UniRef100: UniRef100_P35235
UniRef90: UniRef90_Q06124
UniRef50: UniRef50_Q06124
UniGene: Mm.8681
CCDS: CCDS51637.1, CCDS39247.1

全选

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