Cdk12 - cyclin-dependent kinase 12-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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192350 Cdk12

基因描述

Type	Description
Definition	cyclin-dependent kinase 12

研究结论

Date	Results	Publications
2010-01-21 00:00:00	CDK12 and cyclin L1/L2 are cyclin-dependent kinase and cyclin partners and regulate alternative splicing.	16537916

名称对应

Type	IDs
Synonymous	Crk7, Crkrs, Pksc
Gene	UniProtKB-ID: CDK12_RAT UniprotKB: Q3MJK5 UniParc: UPI00000E5E2C, UPI00005B6162 EMBL: AY072294, AY962568 Ensembl: ENSRNOG00000006000 KO: rno:192350
Nucleutide sequences	EMBL-CDS: AAL69525.1, AAY41734.1 Ensembl_TRS: ENSRNOT00000008256
Protein sequencees	Ensembl_PRO: ENSRNOP00000008256 RefSeq: NP_620271.1, XP_006247313.1, XP_006247312.1, NP_001029039.1
Others	UniRef100: UniRef100_Q3MJK5 UniRef90: UniRef90_Q3MJK5 UniRef50: UniRef50_Q9NYV4 UniGene: Rn.48817

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
23837720	The writers, readers, and functions of the RNA polymerase II C-terminal domain code. Chem. Rev. CÃ©lia Jeronimo , Alain R Bataille , FranÃ§ois Robert	2013-11-13	Cdk7, Cdk12, Ctdp1, Ssu72, Rpap2, Cdc14a, Cdc14b, Cdk9, Ctdsp1, Cdk8
22547058	Cyclin K-containing kinase complexes maintain self-renewal in murine embryonic stem cells. J Biol Chem Qian Dai , Tingjun Lei , Changhong Zhao , Jianqiao Zhong , Yi-zhi Tang , Bin Chen , Jie Yang , Chenghua Li , Siyu Wang , Xu Song , Li Li , Qintong Li	2012-07-20	-
22622228	Updating the RNA polymerase CTD code: adding gene-specific layers. Trends Genet. Sylvain Egloff , Martin Dienstbier , Shona Murphy	2012-07-01	-
22012619	The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes. Genes Dev. Dalibor Blazek , Jiri Kohoutek , Koen Bartholomeeusen , Eric Johansen , Petra Hulinkova , Zeping Luo , Peter Cimermancic , Jernej Ule , B Matija Peterlin	2011-10-15	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
20952539	CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1. Genes Dev Bartlomiej Bartkowiak , Pengda Liu , Hemali P Phatnani , Nicholas J Fuda , Jeffrey J Cooper , David H Price , Karen Adelman , John T Lis , Arno L Greenleaf	2010-10-15	-
19651820	CRK7 modifies the MAPK pathway and influences the response to endocrine therapy. Carcinogenesis Elizabeth Iorns , Sanne R Martens-de Kemp , Christopher J Lord , Alan Ashworth	2009-10-01	-
16537916	Identification and characterization of the CDK12/cyclin L1 complex involved in alternative splicing regulation. Mol. Cell. Biol. Hung-Hsi Chen , Yu-Chiuan Wang , Ming-Ji Fann	2006-04-01	LOC100909712, Ccnl1, Cdk12, Ccnl2
11683387	CrkRS: a novel conserved Cdc2-related protein kinase that colocalises with SC35 speckles. J. Cell. Sci. T K Ko , E Kelly , J Pines	2001-07-01	MBP, CDK12, POLR2A, SRSF1, SRSF2
8889548	Normalization and subtraction: two approaches to facilitate gene discovery. Genome Res. M F Bonaldo , G Lennon , M B Soares	1996-09-01	-

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