| Type | Description |
|---|---|
| Definition | twinfilin actin binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:36:00 | Twinfilin uncaps filament barbed ends to promote turnover of lamellipodial actin networks. | 33558729 |
| 2019-04-13 10:27:00 | The results demonstrate that the conserved C-terminal tail of twinfilin is a multifunctional binding motif, which is crucial for interaction with the heterodimeric capping protein and for tethering twinfilin to phosphoinositide-rich membranes. | 29425097 |
| 2019-03-16 11:01:00 | Here, the authors discover that the C-terminal tail of Twinfilin harbors a capping protein-interacting (CPI) motif, identifying it as a novel CPI-motif protein. Twinfilin binds competitively with CARMIL to capping protein, protecting capping protein from barbed-end displacement by CARMIL. | 30351272 |
| 2015-05-16 10:12:00 | FGF signaling promotes the expansion of A6-expressing liver cells partly via AKT-dependent activation of beta-Catenin expansion of A6(+ive) periportal cells and possibly by reprogramming of centrolobular hepatocytes. | 24365171 |
| 2010-01-21 00:00:00 | structural conservation between its actin monomer-binding sites and the binding site of actin-depolymerizing factor (ADF)/cofilin | 12207032 |
| Type | IDs |
|---|---|
| Synonymous | A6, Ptk9, twinfilin |
| Gene |
UniProtKB-ID:
TWF1_MOUSE
UniprotKB:
Q91YR1
UniParc:
UPI0000021EF7
EMBL:
BC094034,
AK150852,
AY267188,
AK147990,
BC015081,
U82324
Ensembl:
ENSMUSG00000022451
KO:
mmu:19230
|
| Nucleutide sequences |
EMBL-CDS:
AAH94034.1,
BAE28272.1,
AAP31404.1,
AAH15081.1,
BAE29908.1,
AAB66592.1
Ensembl_TRS:
ENSMUST00000023087
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023087
RefSeq:
XP_036015163.1,
XP_006520701.1,
NP_032997.3
|
| Others |
UniRef100:
UniRef100_Q91YR1
UniRef90:
UniRef90_Q12792
UniRef50:
UniRef50_Q12792
UniGene:
Mm.490250
CCDS:
CCDS27773.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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