| Type | Description |
|---|---|
| Definition | prostaglandin-endoperoxide synthase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 11:36:00 | PTGS1-modified cells were incubated with synthograft and transplanted into the dorsal space of mice. .. HE staining showed that the PTGS1sh group generated much more bone-like tissue compared with the NC group , and quantitative analysis verified that silencing of PTGS1 greatly promoted bone-like tissue formation in vivo | 30760327 |
| 2020-01-04 12:40:00 | Platelet-Specific Deletion of Cyclooxygenase-1 Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice | 31248980 |
| 2019-11-02 11:32:00 | Transgenic mice study revealed that knock-in COX-1 failed to substitute for the loss of COX-2 in COX-1>COX-2 mice during implantation, indicating that COX-1 may be replaced by COX-2, but not vice versa. A panel of prostaglandins detected in uterus and ovary demonstrates that prostaglandin biosynthesis preferentially depends on native COX-1, but not COX-2. | 30108257 |
| 2019-07-13 10:56:00 | Expression of COX-1 and production of thromboxane A2 in platelets of STZ-induced diabetic mice were elevated. | 30811756 |
| 2019-05-25 11:51:00 | Manipulation of COXs 1 & 2 revealed isoform-specific compensatory functions and variable degrees of interchangeability for PG biosynthesis in cells/tissues | 29180445 |
| Type | IDs |
|---|---|
| Synonymous | COX1, Cox-1, Cox-3, PGHS-1, PHS 1, Pghs1 |
| Gene |
UniProtKB-ID:
PGH1_MOUSE,
Q543T1_MOUSE
UniprotKB:
P22437,
Q543T1
UniParc:
UPI000000188A
EMBL:
BC005573,
AK170414,
DQ173701,
AK142741,
DQ173712,
DQ173714,
DQ173699,
DQ173708,
AH015270,
DQ173710,
AK159907,
DQ173713,
DQ173704,
AK170664,
DQ173703,
AH015269,
M34141,
CT010314,
DQ173711,
AK138432,
DQ173702,
AK046457,
AK163609,
BC023322,
DQ173700
Ensembl:
ENSMUSG00000047250
KO:
mmu:19224
|
| Nucleutide sequences |
EMBL-CDS:
AAA39913.1,
AAH05573.1,
BAE41945.1,
CAJ18522.1,
ABA19088.1,
BAE23660.1,
AAH23322.2,
BAE37419.1,
BAE25179.1,
BAE41780.1,
BAC32737.1,
ABA19089.1,
BAE35471.1
Ensembl_TRS:
ENSMUST00000062069
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000059977
RefSeq:
NP_032995.1,
XP_006497853.1,
XP_006497857.1,
XP_011237338.1,
XP_006497854.1
|
| Others |
UniRef100:
UniRef100_P22437
UniRef90:
UniRef90_Q63921
UniRef50:
UniRef50_O62698
UniGene:
Mm.275434
CCDS:
CCDS15970.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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