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192206 Prok2

192206

Prok2

prokineticin 2

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition prokineticin 2

研究结论

Date Results Publications
2020-10-10 12:59:00 Activation of the NLRP3 Inflammasome Pathway by Prokineticin 2 in Testicular Macrophages of Uropathogenic Escherichia coli- Induced Orchitis. 31474981
2020-09-26 13:02:00 Prokineticin 2 relieves hypoxia/reoxygenation-induced injury through activation of Akt/mTOR pathway in H9c2 cardiomyocytes. 31899964
2020-07-11 12:54:00 We demonstrated a significant upregulation of PROK2 levels in brain tissues of Abeta1-42 i.c.v. injected rats, transgenic AD mice (Tg2576), and in the hippocampus of AD patients. Additionally, through a pilot study, an approximate twofold increase of PROK2 levels has been proved in the serum of AD patients, compared to the control subjects, identifying a potential blood-based biomarker of the disease. 31766244
2019-07-27 12:49:00 PK2 interference may represent a novel and promising therapeutic strategy for the clinical management of orchitis. 29516577
2017-01-14 10:52:00 Given one of the cognate receptors of prokineticin 2, prokineticin receptor 1 (PKR1) was significantly upregulated in orchitis as discussed in the current study, it is very likely that PK2/PKR1 signaling contribute to the development of inflammation-related testicular diseases. 26490969

名称对应

Type IDs
Synonymous Bv8
Gene
UniProtKB-ID: PROK2_RAT, Q6V8J7_RAT
UniprotKB: Q8R413, Q6V8J7
UniParc: UPI0000182414, UPI000013221A
EMBL: AABR07061532, CH473957, AY348322, AY089984
Ensembl: ENSRNOG00000010898
KO: rno:192206
Nucleutide sequences
EMBL-CDS: AAM09105.1, EDL91440.1, AAR06924.1
Gene_ORFName: rCG_56160
Ensembl_TRS: ENSRNOT00000015075, ENSRNOT00000015058
Protein sequencees
Ensembl_PRO: ENSRNOP00000015075, ENSRNOP00000015058
RefSeq: NP_620207.1, XP_017447917.1, NP_001032630.1
Others
UniRef100: UniRef100_Q8R413, UniRef100_Q6V8J7
UniRef90: UniRef90_Q9QXU7-2, UniRef90_Q9QXU7
UniRef50: UniRef50_Q9QXU7-2, UniRef50_Q9QXU7
UniGene: Rn.211872

全选

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研究热度

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