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192199 Rspo1

192199

Rspo1

R-spondin 1

protein-coding

Mus musculus

基因描述

Type Description
Definition R-spondin 1

研究结论

Date Results Publications
2021-02-13 13:28:00 A novel function of R-spondin1 in regulating estrogen receptor expression independent of Wnt/beta-catenin signaling. 32749219
2020-08-15 19:07:00 Amphiregulin mediates the hormonal regulation on Rspondin-1 expression in the mammary gland. 31610144
2019-11-30 10:16:00 the Rspo3-Lgr5 axis simultaneously regulates both antimicrobial defence and mucosal regeneration 31235935
2019-09-21 11:39:00 blocking Rspo-Lgr4 signaling overcame Lewis lung carcinoma (LLC) resistance to anti-PD-1 therapy and improved the efficacy of PD-1 immunotherapy against B16F10 melanoma, indicating vital roles of Rspo-Lgr4 in host antitumor immunity and a potential therapeutic target in cancer immunotherapy. 29967265
2017-12-02 10:58:00 reciprocal control of antagonistic Wnt signaling pathways by Rspo1 in muscle stem cell progeny is a key step ensuring normal tissue architecture restoration following acute damage. 28273449

名称对应

Type IDs
Synonymous R-spondin, Rspondin
Gene
UniProtKB-ID: RSPO1_MOUSE, B1ASC1_MOUSE
UniprotKB: Q9Z132, B1ASC1
UniParc: UPI0000023015, UPI0000029590
EMBL: AL626775, BC138831, AK132277, AB016768, BC138833
Ensembl: ENSMUSG00000028871
KO: mmu:192199
Nucleutide sequences
EMBL-CDS: BAE21077.1, BAA75640.1, AAI38834.1, AAI38832.1
Ensembl_TRS: ENSMUST00000030687
Protein sequencees
Ensembl_PRO: ENSMUSP00000030687
RefSeq: NP_619624.2, XP_006502925.1
Others
UniRef100: UniRef100_B1ASC1, UniRef100_Q9Z132
UniRef90: UniRef90_Q9Z132
UniRef50: UniRef50_Q2MKA7
UniGene: Mm.42202
CCDS: CCDS18633.1

全选

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研究热度

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