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192195 Ash1l

192195

Ash1l

ASH1 like histone lysine methyltransferase

protein-coding

Mus musculus

基因描述

Type Description
Definition ASH1 like histone lysine methyltransferase

研究结论

Date Results Publications
2021-01-16 15:53:00 Novel role of ASH1L histone methyltransferase in anaplastic thyroid carcinoma. 32398261
2019-08-10 12:42:00 Study shows that mutations associated with acute myelogenous leukemia (AML) result both in loss of miR-142-3p function and in decreased miR-142-5p expression. During hematopoietic maturation, loss of Mir142 increased ASH1L protein expression and consequently resulted in the aberrant maintenance of Hoxa gene expression in myeloid-committed hematopoietic progenitors. 29724719
2019-01-05 11:32:00 The Trithorax protein Ash1L promotes myoblast fusion by activating Cdon expression 30487570
2019-01-05 10:38:00 Ash1l upregulates Smad3 expression by directly targeting Smad3 promoter to increase local H3K4 trimethylation. 28598443
2018-12-01 11:17:00 Loss of Ash1l leads to more proliferative keratinocytes in disturbed differentiation stages and Ash1l mutation leads to delayed re-epithlialization but increased keratinocyte proliferation at the wound edge. 28374742

名称对应

Type IDs
Synonymous 8030453L17Rik, Ash1, E430018P19Rik, Kmt2h
Gene
UniProtKB-ID: ASH1L_MOUSE
UniprotKB: Q99MY8
UniParc: UPI000058B426
EMBL: AK153783, AK088497, AK033177, BC052194, AC140468, AC127377, AK034679, AF247132
Ensembl: ENSMUSG00000028053
KO: mmu:192195
Nucleutide sequences
EMBL-CDS: AAH52194.1, BAE32182.1, AAK26242.1, BAC28795.2, BAC28183.2, BAC40390.1
Ensembl_TRS: ENSMUST00000186583, ENSMUST00000090933
Protein sequencees
Ensembl_PRO: ENSMUSP00000088451, ENSMUSP00000140251
RefSeq: XP_030108328.1, XP_036018849.1, XP_017174988.1, XP_006501205.1, XP_036018850.1, XP_006501204.1, NP_619620.3, XP_017174991.1
Others
UniRef100: UniRef100_Q99MY8
UniRef90: UniRef90_Q99MY8
UniRef50: UniRef50_Q9NR48
UniGene: Mm.130752
CCDS: CCDS17487.1

全选

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