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192173 Mcrip1

192173

Mcrip1

MAPK regulated corepressor interacting protein 1

protein-coding

Mus musculus

基因描述

Type Description
Definition MAPK regulated corepressor interacting protein 1

研究结论

Date Results Publications
2020-05-02 10:21:00 MCRIP1 interferes with interactions of CtBP with the lung-enriched transcriptional repressors, Foxp1 and Foxp2, thereby preventing the recruitment of the CtBP co-repressor complex to the SP-B and SP-C promoters and maintaining them in an active chromatin state. Homozygous deficiency of Mcrip1 in mice causes fatal respiratory distress due to abnormal transcriptional repression of surfactant proteins. 31240265

名称对应

Type IDs
Synonymous Fam195b
Gene
UniProtKB-ID: MCRI1_MOUSE
UniprotKB: Q3UGS4
UniParc: UPI00001C4CEF
EMBL: CH466558, BC025536, AL669855, AK147780
Ensembl: ENSMUSG00000061111
KO: mmu:192173
Nucleutide sequences
EMBL-CDS: AAH25536.1, EDL34763.1, BAE28133.1
Ensembl_TRS: ENSMUST00000034913
Protein sequencees
Ensembl_PRO: ENSMUSP00000034913
RefSeq: NP_001028403.1, NP_001360863.1
Others
UniRef100: UniRef100_Q3UGS4
UniRef90: UniRef90_Q3UGS4
UniRef50: UniRef50_Q3UGS4
UniGene: Mm.262300
CCDS: CCDS36391.1

全选

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研究热度

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