| Type | Description |
|---|---|
| Definition | pre-mRNA processing factor 8 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-05 10:44:00 | Knockdown of PRPF8 significantly impairs mitophagosome formation and subsequent mitochondrial clearance through the aberrant mRNA splicing of ULK1, which mediates macroautophagy/autophagy initiation. | 30103670 |
| 2016-05-07 10:43:00 | The mouse retinal pigment epithelium (RPE)is the primary cell affected by mutations in the RNA splicing factors (PRPF3, PRPF8, and PRPF31), and these changes occur at an early age. | 25111227 |
| 2011-08-06 10:37:00 | found that PRP31 and PRPC8 as well as snRNAs are highly expressed in retinal cells | 21283520 |
| 2011-02-12 11:16:00 | The finding of similar degenerative changes in RPE cells of all three mouse models suggests that the retinal pigment epithelium may be the primary cell type affected in the RNA splicing factor forms of retinitis pigmentosa. | 20811066 |
| Type | IDs |
|---|---|
| Synonymous | AU019467, D11Bwg0410e, DBF3/PRP8, Prp8, Sfprp8l |
| Gene |
UniProtKB-ID:
PRP8_MOUSE,
Q3UNG1_MOUSE
UniprotKB:
Q99PV0,
Q3UNG1
UniParc:
UPI0000180944,
UPI00005AC2B2
EMBL:
BC034648,
BC093481,
BC054103,
AK144232,
AK041017,
AB047391,
AL591496
Ensembl:
ENSMUSG00000020850
KO:
mmu:192159
|
| Nucleutide sequences |
EMBL-CDS:
AAH54103.1,
BAC30783.1,
AAH93481.1,
BAB32671.1,
AAH34648.1,
BAE25786.1
Ensembl_TRS:
ENSMUST00000102510,
ENSMUST00000018449
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099568,
ENSMUSP00000018449
RefSeq:
NP_619600.2
|
| Others |
UniRef100:
UniRef100_Q99PV0,
UniRef100_Q3UNG1
UniRef90:
UniRef90_Q3UNG1,
UniRef90_Q6P2Q9
UniRef50:
UniRef50_Q6P2Q9,
UniRef50_Q3UNG1
UniGene:
Mm.3757
CCDS:
CCDS25048.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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