| Type | Description |
|---|---|
| Definition | suppressor of cytokine signaling 7 |
| Date | Results | Publications |
|---|---|---|
| 2018-02-03 10:59:00 | Results suggest: 1) SOCS6 and SOCS7 bind tyrosine-phosphorylated DAB1 and commit it to ubiquitination and proteasomal degradation. 2) Removal of phosphorylated DAB1 by SOCS6 and SOCS7 terminates reelin signaling and allows a new cycle of reelin signaling to commence. 3) Repeated cycles of reelin signaling "ON" and "OFF" drive the fundamentally cyclic process of cell migration in the cortex. | 26503265 |
| 2010-01-21 00:00:00 | prominent expression of Socs7 in the brain suggests an important functional role of SOCS7 in this organ | 15494444 |
| 2010-01-21 00:00:00 | Data implicate SOCS7 in the modulation of allergic inflammation and demonstrate that SOCS7 is involved in the regulation of TSLP signaling in mast cells. | 19427817 |
| 2010-01-21 00:00:00 | SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation(SOCS-6) | 12052866 |
| 2010-01-21 00:00:00 | data suggest that SOCS7 is a potent regulator of glucose homeostasis and insulin signaling | 16127460 |
| Type | IDs |
|---|---|
| Synonymous | 2310063P06Rik, C85125, Nap4 |
| Gene |
UniProtKB-ID:
SOCS7_MOUSE
UniprotKB:
Q8VHQ2
UniParc:
UPI0000029462
EMBL:
AK147580,
AK147650,
AF424814,
AL596088
Ensembl:
ENSMUSG00000038485
KO:
mmu:192157
|
| Nucleutide sequences |
EMBL-CDS:
BAE28006.1,
BAE28049.1,
AAL60516.1
Ensembl_TRS:
ENSMUST00000045540
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000040896
RefSeq:
NP_619598.2,
XP_006532591.1,
XP_006532592.1
|
| Others |
UniRef100:
UniRef100_Q8VHQ2
UniRef90:
UniRef90_Q8VHQ2
UniRef50:
UniRef50_O14512
UniGene:
Mm.34339
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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