| Type | Description |
|---|---|
| Definition | surfactant protein B |
| Date | Results | Publications |
|---|---|---|
| 2019-01-26 12:28:00 | The expression of SP-B and SP-C in GDM group was significantly reduced as compared with control group (P<0.05)... It was concluded that gestational diabetes mellitus can cause fetal lung development and maturation disorders, and FOXA2 in fetal lung tissue decreases while nitrocellulose FOXA2 increases | 30341519 |
| 2017-10-28 12:06:00 | SP-B is present on the surface of exocytosed surfactant particles. Antibodies against SP-B stabilize the released particles when contacting the air-liquid interface, precluding their transformation and the formation of surface films. SP-B acts as an essential, preformed molecular key in the initial stages of surfactant unpacking and surface film formation. | 27155084 |
| 2015-12-19 11:41:00 | Liraglutide activates the GLP1 receptor, increasing ACE2 expression, reversing right ventricle hypertrophy, and improving the production of SP-A and SP-B in the lungs of Type 1 Diabetes rats | 26196539 |
| 2010-03-22 11:30:00 | The role of the SP-B NH(2) terminus in the formation and stability of cylindrical structures, specifically the distribution of lipid stack height, width, and density with four SP-B truncation peptides, was studied. | 20023175 |
| 2010-01-21 00:00:00 | alterations of surfactant are a consequence of the ventilation strategy that impair the biophysical activity of this material and thereby contribute directly to lung dysfunction over time | 18344412 |
| Type | IDs |
|---|---|
| Synonymous | Sp-b |
| Gene |
UniProtKB-ID:
PSPB_RAT
UniprotKB:
P22355
UniParc:
UPI00001327F8
EMBL:
X14778
KO:
rno:192155
|
| Nucleutide sequences |
EMBL-CDS:
CAA32885.1
|
| Protein sequencees |
RefSeq:
XP_006236719.1,
NP_620197.2
|
| Others |
UniRef100:
UniRef100_P22355
UniRef90:
UniRef90_P22355
UniRef50:
UniRef50_P22355
UniGene:
Rn.1952
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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